STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSL2367Putative methyl-accepting chemotaxis protein; C-terminal region is similar to the N-terminal region of Salmonella typhimurium methyl-accepting chemotaxis protein II Tar or CheM SWALL:MCP2_SALTY (SWALL:P02941) (553 aa) fasta scores: E(): 1.9e-45, 44.1% id in 390 aa, and to an internal region of Ralstonia solanacearum probable methyl-accepting chemotaxis I MCP-I serine chemoreceptor transmembrane protein rsp0507 or rs00386 SWALL:Q8XSG9 (EMBL:AL646079) (600 aa) fasta scores: E(): 5.3e-47, 39.06% id in 535 aa. (640 aa)    
Predicted Functional Partners:
cheA
Chemotaxis two-component sensor kinase CheA; Similar to Escherichia coli chemotaxis protein CheA or b1888 SWALL:CHEA_ECOLI (SWALL:P07363) (654 aa) fasta scores: E(): 9.5e-76, 56.14% id in 741 aa.
 
 0.990
cheW2
Chemotaxis protein CheW2; Similar to Escherichia coli, and Escherichia coli O157:H7 chemotaxis protein CheW or b1887 or z2941 or ecs2597 SWALL:CHEW_ECOLI (SWALL:P07365) (167 aa) fasta scores: E(): 4.1e-30, 59.86% id in 147 aa, and to Burkholderia pseudomallei chemotaxis protein CheW SWALL:O05183 (EMBL:U92493) (175 aa) fasta scores: E(): 9.4e-32, 57.31% id in 164 aa. Note: Also similar to BPSL3305 cheW (176 aa) fasta scores: E(): 9.3e-31, 60.131% identity in 153 aa overlap.
 
 0.986
cheW
Chemotaxis protein CheW; Previously characterised as Burkholderia pseudomallei chemotaxis protein CheW SWALL:O05183 (EMBL:U92493) (175 aa) fasta scores: E(): 2.1e-66, 100% id in 175 aa, and to Escherichia coli chemotaxis protein CheW or b1887 or z2941 or ecs2597 SWALL:CHEW_ECOLI (SWALL:P07365) (167 aa) fasta scores: E(): 9.8e-39, 71.81% id in 149 aa.
 
 0.986
cheB
Chemotaxis protein-glutamate methylesterase protein CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.985
cheR
Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 0.984
cheD
Putative chemotaxis protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  0.978
BPSS1871
Putative chemotaxis-related histidine kinase protein; Similar to Thermotoga maritima chemotaxis protein CheA or tm0702 SWALL:CHEA_THEMA (SWALL:Q56310) (671 aa) fasta scores: E(): 2.2e-33, 27.4% id in 708 aa, and to Rhizobium loti chemotaxis histidine kinase mll9511 SWALL:Q98PD0 (EMBL:AP003017) (757 aa) fasta scores: E(): 1.1e-104, 49.07% id in 864 aa.
 
 
 0.909
cheY1
Chemotaxis two-component response regulator CheY1; Similar to Rhizobium meliloti chemotaxis regulator CheY or R00638 or Smc03006 SWALL:Q52879 (EMBL:U13166) (121 aa) fasta scores: E(): 7.1e-15, 43.8% id in 121 aa.
  
  0.899
cheB2
Putative chemotaxis-related methylesterase protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.818
BPSS1873
Similar to Ralstonia solanacearum putative methyltransferase protein rsp1647 or rs02206 SWALL:Q8XPJ3 (EMBL:AL646086) (466 aa) fasta scores: E(): 1.3e-45, 37.71% id in 684 aa, and to Myxococcus xanthus protein methyltransferase FrzF SWALL:FRZF_MYXXA (SWALL:P31759) (593 aa) fasta scores: E(): 7.1e-08, 27.28% id in 546 aa.
 
 
 0.810
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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