STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (433 aa)    
Predicted Functional Partners:
selA
L-seryl-tRNA(SeC) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
     
 0.930
cysS
Similar to Escherichia coli cysteinyl-tRNA synthetase CysS or b0526 SWALL:SYC_ECOLI (SWALL:P21888) (461 aa) fasta scores: E(): 4.5e-95, 55.88% id in 467 aa, and to Ralstonia solanacearum cysteinyl-tRNA synthetase rsc1167 or rs04577 SWALL:SYC_RALSO (SWALL:Q8Y077) (465 aa) fasta scores: E(): 7.8e-137, 74.4% id in 465 aa; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.840
thrS
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
  
 
 0.799
tyrZ
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
 
  
 0.794
valS
Putative valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
 
  
 0.790
hisS
histidyl-tRNA synthetase; Similar to Escherichia coli, and Escherichia coli O157:H7 histidyl-tRNA synthetase HisS or b2514 or z3777 or ecs3376 SWALL:SYH_ECOLI (SWALL:P04804) (423 aa) fasta scores: E(): 1.2e-82, 54.52% id in 420 aa, and to Ralstonia solanacearum probable histidine-tRNA synthetase protein HisS or rsc1216 or rs02790 SWALL:Q8Y029 (EMBL:AL646063) (432 aa) fasta scores: E(): 1e-130, 75.4% id in 435 aa.
 
 
 0.766
BPSL0077
Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
    0.753
glyS
Similar to Escherichia coli glycyl-tRNA synthetase beta chain GlyS or GlyS(B) or b3559 SWALL:SYGB_ECOLI (SWALL:P00961) (688 aa) fasta scores: E(): 1.6e-102, 44.5% id in 692 aa, and to Ralstonia solanacearum glycyl-tRNA synthetase beta chain glyS or rsc0524 or rs04944 SWALL:Q8Y213 (EMBL:AL646059) (697 aa) fasta scores: E(): 1.2e-166, 64.56% id in 697 aa, and to Neisseria meningitidis glycyl-tRNA synthetase beta chain glyS or nma0523 SWALL:Q9JW67 (EMBL:AL162753) (687 aa) fasta scores: E(): 2.9e-123, 51.36% id in 695 aa.
  
  
 0.751
lysS
lysyl-tRNA synthetase; Similar to Escherichia coli, and Escherichia coli O6 lysyl-tRNA synthetase LysS or HerC or AsuD SWALL:SYK1_ECOLI (SWALL:P13030) (504 aa) fasta scores: E(): 3.9e-116, 57.82% id in 505 aa, and to Ralstonia solanacearum putative lysyl-tRNA synthetase protein rsc1028 or rs04223 SWALL:Q8Y0L5 (EMBL:AL646062) (510 aa) fasta scores: E(): 2.3e-173, 81.96% id in 510 aa; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.733
ileS2
Putative isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
 
  
 0.683
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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