STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmhAPutative sedoheptulose 7-phosphate isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (197 aa)    
Predicted Functional Partners:
wcbL
Putative sugar kinase; Similar to Aneurinibacillus thermoaerophilus D-glycero-d-manno-heptose 7-phosphate kinase GmhB SWALL:Q9AGY8 (EMBL:AF324836) (341 aa) fasta scores: E(): 1.6e-79, 55.84% id in 342 aa. Previously sequenced Burkholderia pseudomallei putative sugar kinase WcbL SWALL:Q93UJ3 (EMBL:AF228583) (346 aa) fasta scores: E(): 5.3e-139, 100% id in 346 aa.
 
 0.999
wcbN
Similar to Aneurinibacillus thermoaerophilus D-glycero-d-manno-heptose 1,7-bisphosphate phosphatase GmhC SWALL:Q9AGY5 (EMBL:AF324836) (179 aa) fasta scores: E(): 3.6e-35, 60% id in 155 aa. Identical to Burkholderia mallei WcbN protein SWALL:Q9AI34 (EMBL:AF285636) (189 aa) fasta scores: E(): 9.5e-78, 100% id in 189 aa.
  
 0.997
waaE
Putative ADP-heptose synthase; Previously sequenced as Burkholderia pseudomallei putative ADP-heptose synthase WaaE SWALL:Q9WWX7 (EMBL:AF159428) (307 aa) fasta scores: E(): 3.8e-113, 100% id in 307 aa, and to Haemophilus influenzae ADP-heptose synthase RfaE or WaaE or hi1526 SWALL:RFAE_HAEIN (SWALL:O05074) (476 aa) fasta scores: E(): 9.1e-47, 49% id in 302 aa and to Escherichia coli ADP-heptose synthase RfaE or waae or b3052 SWALL:RFAE_ECOLI (SWALL:P76658) (477 aa) fasta scores: E(): 8.8e-46, 49.19% id in 309 aa.
 
  
 0.980
BPSL0395
Putative cytidylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
   
 0.978
BPSL0666
Putative hydrolase/phosphatase protein; Similar to Pseudomonas fluorescens hisB-like protein SWALL:Q9F729 (EMBL:AF286536) (213 aa) fasta scores: E(): 1e-33, 54.85% id in 175 aa, and to Ralstonia solanacearum putative phosphatase protein rsc0523 or rs04957 SWALL:Q8Y214 (EMBL:AL646059) (199 aa) fasta scores: E(): 7.2e-49, 72.62% id in 179 aa, and to Neisseria meningitidis putative phosphatase nma0405 SWALL:Q9JWE9 (EMBL:AL162753) (187 aa) fasta scores: E(): 2.5e-36, 56.98% id in 179 aa.
  
 0.977
wcbM
Similar to Aneurinibacillus thermoaerophilus D-glycero-d-manno-heptose 1-phosphate guanosyltransferase GmhD SWALL:Q9AGY6 (EMBL:AF324836) (230 aa) fasta scores: E(): 4.6e-29, 39.55% id in 225 aa. Previously sequenced Burkholderia pseudomallei putative capsular polysaccharide biosynthesis protein WcbM SWALL:Q93UJ1 (EMBL:AF228583) (230 aa) fasta scores: E(): 5e-89, 99.56% id in 230 aa.
 
  
 0.955
wcbJ
Similar to Azorhizobium caulinodans putative capsular polysaccharide biosynthesis protein Oac2 SWALL:Q06936 (EMBL:Z22611) (296 aa) fasta scores: E(): 1.7e-06, 27.13% id in 199 aa. Identical to Burkholderia mallei putative capsular polysaccharide biosynthesis protein WcbJ SWALL:Q9AI39 (EMBL:AF285636) (280 aa) fasta scores: E(): 1.2e-109, 100% id in 280 aa.
     
 0.942
BPSS2256
Putative haloacid dehalogenase-like hydrolase; Similar to Yersinia pestis hypothetical protein ypo1074 SWALL:Q8ZH37 (EMBL:AJ414146) (188 aa) fasta scores: E(): 4.2e-15, 32.75% id in 174 aa, and to Escherichia coli and Shigella flexneri hypothetical protein YaeD SWALL:YAED_ECOLI (SWALL:P31546) (191 aa) fasta scores: E(): 1.2e-14, 35.03% id in 157 aa. CDS is extended at the C-terminus in comparison to some orthologues.
  
 0.939
BPSL3273
Putative phosphosugar isomerase; Similar to Pseudomonas aeruginosa probable phosphoheptose isomerase Pa4425 SWALL:Q9HVZ0 (EMBL:AE004857) (197 aa) fasta scores: E(): 3.4e-25, 45.55% id in 191 aa, and to Burkholderia pseudomallei GmhA SWALL:Q93UJ2 (EMBL:AF228583) (197 aa) fasta scores: E(): 6.5e-15, 35.97% id in 189 aa, and to Aneurinibacillus thermoaerophilus sedoheptulose 7-phosphate isomerase GmhA SWALL:Q9AGY7 (EMBL:AF324836) (198 aa) fasta scores: E(): 2.2e-13, 35.75% id in 193 aa.
  
  
 
0.918
BPSS2244
Similar to Nostoc punctiforme putative sucrose-phosphate synthase SpsA SWALL:Q937E5 (EMBL:AJ316587) (423 aa) fasta scores: E(): 1.1e-44, 36.34% id in 421 aa, and to Mycobacterium tuberculosis hypothetical protein rv0486 or mt0504 or mtcy20g9.12 SWALL:Y486_MYCTU (SWALL:Q11152) (480 aa) fasta scores: E(): 8.9e-24, 36.23% id in 425 aa.
  
 0.915
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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