STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (203 aa)    
Predicted Functional Partners:
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.977
zapD
Conserved hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
  
    0.936
acpS
Putative holo-[acyl-carrier protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
    
 0.913
BPSL2345
Hypothetical protein; Weakly similar to Anabaena sp. 4'-phosphopantetheinyl transferase HetI or all5359 SWALL:HETI_ANASP (SWALL:P37695) (237 aa) fasta scores: E(): 9e-12, 31.57% id in 209 aa, and to the N-terminal region of Streptomyces venezuelae phosphopantetheinyl transferase JadM SWALL:Q9L7M4 (EMBL:AF222693) (262 aa) fasta scores: E(): 1.1e-10, 34.89% id in 235 aa.
     
 0.904
BPSS2266
Similar to Anabaena sp. 4'-phosphopantetheinyl transferase HetI SWALL:HETI_ANASP (SWALL:P37695) (237 aa) fasta scores: E(): 7.9e-15, 31.5% id in 200 aa, and to Stigmatella aurantiaca MtaA protein SWALL:Q9RFL1 (EMBL:AF188287) (277 aa) fasta scores: E(): 1.5e-37, 43.08% id in 253 aa.
     
 0.904
gspO
Type IV prepilin leader peptide type M1; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
  
  
 0.887
mutM
Putative formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.784
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
  
 0.769
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
 
    0.707
BPSL3008
Similar to Aeromonas hydrophila type IV pilus assembly protein TapB SWALL:TAPB_AERHY (SWALL:P45792) (568 aa) fasta scores: E(): 1.3e-64, 51.04% id in 382 aa.
     
 0.706
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.