STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
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[Homology]
Score
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (398 aa)    
Predicted Functional Partners:
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
 
 0.999
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
 
 0.946
BPSL2472
Similar to Ralstonia solanacearum putative prolin-rich transmembrane protein rsc3315 or rs02545 SWALL:Q8XU78 (EMBL:AL646074) (787 aa) fasta scores: E(): 3.3e-65, 45.09% id in 825 aa.
  
 
 0.933
ftsQ
Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
  
  
 0.905
minC
Probable septum site-determining protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
   
 
 0.903
mreB
Putative rod shape-determining protein; Similar to Escherichia coli, Salmonella typhimurium, and Salmonella typhi rod shape-determining protein MreB or EnvB or RodY SWALL:MREB_ECOLI (SWALL:P13519) (347 aa) fasta scores: E(): 1.7e-87, 71.14% id in 350 aa, and to Ralstonia solanacearum probable rod shape-determining protein rsc0059 or rs01882 SWALL:Q8Y3C1 (EMBL:AL646057) (347 aa) fasta scores: E(): 1.9e-114, 93.66% id in 347 aa. Similar to BPSS0633, 54.955% identity (54.955% ungapped) in 333 aa overlap.
  
 
 0.871
ftsW
Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
 
 
 0.858
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
 
 0.850
BPSL2165
Putative membrane protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
  
 
 0.847
mreB-2
Rod shape-determining protein; Similar to Escherichia coli, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri rod shape-determining protein MreB SWALL:MREB_ECOLI (SWALL:P13519) (347 aa) fasta scores: E(): 3.8e-57, 51.43% id in 348 aa, and to Ralstonia solanacearum probable rod shape-determining protein rsc0059 or rs01882 SWALL:Q8Y3C1 (EMBL:AL646057) (347 aa) fasta scores: E(): 3.5e-63, 54.95% id in 333 aa. Similar to BPSL0186, 54.955% identity (54.955% ungapped) in 333 aa overlap.
  
 
 0.830
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.