STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
aqpZAquaporin Z; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family. (234 aa)    
Predicted Functional Partners:
glpK
Putative glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.858
BPSL2973
Putative exported protein; No significant database matches.
   
 
 0.790
glpD
Similar to Pseudomonas aeruginosa glycerol-3-phosphate dehydrogenase GlpD or pa3584 SWALL:GLPD_PSEAE (SWALL:P52111) (512 aa) fasta scores: E(): 9.6e-105, 57.91% id in 480 aa, and to Xanthomonas axonopodis glycerol-3-phosphate dehydrogenase GlpD or xac0360 SWALL:AAM35252 (EMBL:AE011662) (501 aa) fasta scores: E(): 5.5e-117, 63.25% id in 479 aa, and to Xanthomonas campestris glycerol-3-phosphate dehydrogenase GlpD or xcc0360 SWALL:AAM39679 (EMBL:AE012132) (508 aa) fasta scores: E(): 5.5e-116, 61.38% id in 505 aa; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.781
BPSL2712
Putative hydrolase; Similar to Ralstonia solanacearum putative glycerophosphoryl diester phosphodiesterase, periplasmic precursor protein GlpQ or rsc0502 or rs05020 SWALL:Q8Y234 (EMBL:AL646059) (378 aa) fasta scores: E(): 4.4e-95, 68.66% id in 383 aa, and to Xanthomonas campestris glycerophosphoryl diester phosphodiesterase GlpQ or xcc4234 SWALL:AAM43450 (EMBL:AE012551) (370 aa) fasta scores: E(): 1.5e-65, 55.75% id in 339 aa.
  
 
 0.735
BPSL0570
Similar to Thermoplasma acidophilum hypothetical protein TA0489 SWALL:Q9HKV4 (EMBL:AL445064) (231 aa) fasta scores: E(): 4.9e-10, 25.41% id in 240 aa, and to Thermoplasma volcanium hypothetical protein TV0582 or tvg0571216 SWALL:Q97B75 (EMBL:AP000992) (232 aa) fasta scores: E(): 3e-07, 24.78% id in 230 aa.
    
 
 0.706
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.702
dnaJ
Putative DnaJ chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]
   
 
 0.635
BPSL0215
Aldo/keto reductase family protein; Similar to Xanthomonas axonopodis oxidoreductase XAC3199 SWALL:AAM38043 (EMBL:AE011965) (346 aa) fasta scores: E(): 7.6e-104, 77.03% id in 344 aa, and to Mus musculus voltage-gated potassium channel beta-2 subunit KCNAB2 or KCNB3 or CKbeta2 SWALL:KVB2_MOUSE (SWALL:Q64284) (367 aa) fasta scores: E(): 1.2e-30, 35.93% id in 320 aa.
   
 
 0.520
BPSL1848
Putative oxidoreductase; Similar to Pseudomonas aeruginosa probable oxidoreductase pa4434 SWALL:Q9HVY1 (EMBL:AE004857) (345 aa) fasta scores: E(): 2.3e-78, 58% id in 350 aa, and to Escherichia coli Tas protein or b2834 SWALL:TAS_ECOLI (SWALL:Q46933) (346 aa) fasta scores: E(): 4.6e-75, 56.28% id in 350 aa.
   
 
 0.520
BPSS0353
Putative potassium channel subunit; Similar to the C-terminal region of Homo sapiens voltage-gated potassium channel beta-2 subunit KCNAB2 or KCNA2b or KCNK2 SWALL:KVB2_HUMAN (SWALL:Q13303) (367 aa) fasta scores: E(): 4.2e-56, 45.79% id in 321 aa, and to Xanthomonas campestris voltage-gated potassium channel beta subunit XCC0766 SWALL:AAM40081 (EMBL:AE012176) (322 aa) fasta scores: E(): 5.7e-62, 52.97% id in 319 aa.
   
 
 0.520
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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