STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
adcAcetoacetate decarboxylase; Catalyzes the conversion of acetoacetate to acetone and carbon dioxide; Belongs to the ADC family. (246 aa)    
Predicted Functional Partners:
BPSS0017
Similar to Rhizobium meliloti D-beta-hydroxybutyrate dehydrogenase BdhA or rb1136 or smb21010 SWALL:BDHA_RHIME (SWALL:O86034) (258 aa) fasta scores: E(): 2.1e-28, 40.84% id in 262 aa, and to Ralstonia solanacearum probable dehydrogenase/reductase oxidoreductase protein rsp1059 or rs02396 SWALL:Q8XR09 (EMBL:AL646082) (261 aa) fasta scores: E(): 7.1e-76, 83.14% id in 261 aa. Note: Also similar to BPSS0354 (268 aa) fasta scores: E(): 1.6e-83, 99.615% identity in 260 aa overlap; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
  0.983
BPSS0354
Similar to Rhizobium meliloti D-beta-hydroxybutyrate dehydrogenase BdhA or rb1136 or smb21010 SWALL:BDHA_RHIME (SWALL:O86034) (258 aa) fasta scores: E(): 5.6e-27, 40.45% id in 262 aa, and to Alcaligenes eutrophus D-beta-hydroxybutyrate dehydrogenase HbdH1 SWALL:BDHA_ALCEU (SWALL:Q9X6U2) (258 aa) fasta scores: E(): 1.7e-22, 36.68% id in 259 aa. Note: Also similar to BPSS0017 (262 aa) fasta scores: E(): 3.7e-83, 99.615% identity in 260 aa overlap; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
  0.957
scoA
Similar to Helicobacter pylori succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A ScoA or hp0691 SWALL:SCOA_HELPY (SWALL:P56006) (232 aa) fasta scores: E(): 6.8e-52, 60.17% id in 231 aa, and to Xanthomonas campestris succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A LpsI or WxcI or xcc0627 SWALL:SCOA_XANCP (SWALL:O34264) (242 aa) fasta scores: E(): 8.2e-73, 80.6% id in 232 aa.
    
 0.924
scoB
Similar to Helicobacter pylori succinyl-CoA:3-ketoacid-coenzyme A transferase subunit C ScoB or hp0692 SWALL:SCOB_HELPY (SWALL:P56007) (207 aa) fasta scores: E(): 3.2e-47, 63.41% id in 205 aa, and to Xanthomonas campestris succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B LpsJ or WxcJ or xcc0628 SWALL:SCOB_XANCP (SWALL:O34263) (213 aa) fasta scores: E(): 9.1e-60, 77.51% id in 209 aa.
    
 0.916
BPSL0333
Similar to Homo sapiens hydroxymethylglutaryl-CoA lyase, mitochondrial precursor HMGCL SWALL:HMGL_HUMAN (SWALL:P35914) (325 aa) fasta scores: E(): 3.2e-58, 55.1% id in 294 aa, and to Ralstonia solanacearum putative hydroxymethylglutaryl-CoA lyase protein rsc0261 or rs00696 SWALL:Q8Y2S4 (EMBL:AL646058) (309 aa) fasta scores: E(): 3.2e-85, 78.59% id in 299 aa. CDS is truncated at the N-terminus in comparison to the other proteins, including the human hydroxymethylglutaryl-CoA lyase.
  
  
  0.911
BPSS0840
Similar to Bacillus subtilis sorbitol dehydrogenase GutB SWALL:DHSO_BACSU (SWALL:Q06004) (352 aa) fasta scores: E(): 1.1e-25, 30.25% id in 347 aa, and to Ralstonia solanacearum probable zinc-dependent alcohol dehydrogenase oxidoreductase protein rsc0194 or rs00626 SWALL:Q8Y2Y7 (EMBL:AL646058) (345 aa) fasta scores: E(): 1.1e-97, 73.46% id in 343 aa.
    
  0.900
BPSS0016
Similar to Ralstonia solanacearum putative transmembrane protein rsp1060 or rs02397 SWALL:Q8XR08 (EMBL:AL646082) (377 aa) fasta scores: E(): 2.7e-87, 62.29% id in 366 aa, and to Rhizobium loti hypothetical protein mlr2398 SWALL:Q98IH7 (EMBL:AP002999) (390 aa) fasta scores: E(): 3.1e-65, 49.2% id in 378 aa.
 
   
 0.869
BPSL2018
Putative acid phosphatase; Similar to Burkholderia pseudomallei acid phosphatase AcpA SWALL:Q9L5C5 (EMBL:AF252862) (577 aa) fasta scores: E(): 5.5e-101, 55.68% id in 537 aa, and to Ralstonia solanacearum putative acid phosphatase protein rsp1174 or rs05064 SWALL:Q8XQP7 (EMBL:AL646083) (715 aa) fasta scores: E(): 1.1e-96, 63.1% id in 515 aa.
  
     0.561
BPSL1457
Conserved hypothetical protein; C-terminal region similar to Ralstonia solanacearum putative transmembrane protein rsp1650 or rs02209 SWALL:Q8XPJ0 (EMBL:AL646086) (276 aa) fasta scores: E(): 6.9e-20, 46.89% id in 209 aa, and to Rhizobium loti hypothetical protein mlr3808 SWALL:Q98FE7 (EMBL:AP003002) (301 aa) fasta scores: E(): 1.3e-15, 34.97% id in 243 aa. Note: Contains a 14xSD(V/M)PV repeat.
  
     0.475
acpA
Acid phosphatase; Previously described as Burkholderia pseudomallei acid phosphatase AcpA SWALL:Q9L5C5 (EMBL:AF252862) (577 aa) fasta scores: E(): 0, 99.48% id in 577 aa.
  
     0.472
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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