STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pxpA2LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (266 aa)    
Predicted Functional Partners:
BPSL0259
Similar to Ralstonia solanacearum hypothetical protein rsc2171 or rs01428 SWALL:Q8XXE3 (EMBL:AL646068) (215 aa) fasta scores: E(): 1.5e-50, 63.67% id in 212 aa, and to Salmonella typhimurium putative carboxylase stm0712 SWALL:Q8ZQV8 (EMBL:AE008729) (218 aa) fasta scores: E(): 6.4e-42, 55.18% id in 212 aa.
 
 0.995
BPSL0258
Similar to Ralstonia solanacearum hypothetical protein rsc2170 or rs01429 SWALL:Q8XXE4 (EMBL:AL646068) (353 aa) fasta scores: E(): 3.2e-32, 54.44% id in 360 aa, and to an internal region of Saccharomyces cerevisiae urea amidolyase [includes: urea carboxylase; allophanate hydrolase] DUR1,2 SWALL:DUR1_YEAST (SWALL:P32528) (1835 aa) fasta scores: E(): 2.4e-15, 32.19% id in 351 aa.
 
 0.991
BPSS0195
Similar to Pseudomonas aeruginosa hypothetical protein pa0495 SWALL:Q9I623 (EMBL:AE004486) (292 aa) fasta scores: E(): 5.2e-84, 69.55% id in 289 aa, and to parts of Pseudomonas fluorescens urea amidolyase homologue UahA SWALL:Q9XAV3 (EMBL:AJ243652) (1213 aa) fasta scores: E(): 4.9e-13, 26.18% id in 275 aa.
 
  
 0.981
BPSS0194
Similar to Pseudomonas aeruginosa hypothetical protein pa0496 SWALL:Q9I622 (EMBL:AE004486) (325 aa) fasta scores: E(): 4.1e-81, 65.2% id in 319 aa, and similar to parts of Pseudomonas fluorescens urea amidolyase homologue UahA SWALL:Q9XAV3 (EMBL:AJ243652) (1213 aa) fasta scores: E(): 2.4e-34, 42.76% id in 311 aa.
  
 0.980
pxpA1
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
  
 
0.912
BPSL0001
Conserved hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
  0.900
gshA-2
Similar to Escherichia coli glutamate--cysteine ligase GshA or Gsh-I SWALL:GSH1_ECOLI (SWALL:P06980) (518 aa) fasta scores: E(): 2.1e-70, 41.74% id in 515 aa, and to Pseudomonas aeruginosa glutamate--cysteine ligase pa5203 SWALL:Q9HTY6 (EMBL:AE004933) (527 aa) fasta scores: E(): 1.3e-117, 59.73% id in 529 aa; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
  0.900
BPSL0416
Zinc-binding dehydrogenase (fragment); PS00228 Tubulin-beta mRNA autoregulation signal.
     
  0.900
gshA
Glutamate--cysteine ligase; Similar to Thiobacillus ferrooxidans glutamate--cysteine ligase GshA SWALL:Q56277 (EMBL:U81808) (436 aa) fasta scores: E(): 3.8e-78, 50.59% id in 419 aa, and to Ralstonia solanacearum hypothetical protein rsc0344 or rs03311 SWALL:Q8Y2J1 (EMBL:AL646058) (431 aa) fasta scores: E(): 2e-125, 71.86% id in 430 aa.
     
  0.900
BPSL0671
Conserved hypothetical protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
    
  0.900
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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