STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acoEAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)    
Predicted Functional Partners:
BPSL0890
Putative citrate synthase; C-terminal region is similar to Agrobacterium tumefaciens citrate synthase CisZ or atu4851 or agr_l_71 SWALL:Q8U6F6 (EMBL:AE009414) (335 aa) fasta scores: E(): 6.7e-14, 42.68% id in 335 aa, and to Staphylococcus aureus citrate synthase II CitZ SWALL:Q99TG7 (EMBL:AP003363) (373 aa) fasta scores: E(): 4.7e-13, 27.36% id in 391 aa. Possible alternative translational start site.
  
 0.959
prpC
Similar to Escherichia coli 2-methylcitrate synthase PrpC or b0333 SWALL:PRPC_ECOLI (SWALL:P31660) (389 aa) fasta scores: E(): 3.5e-119, 78.61% id in 374 aa, and to Burkholderia sacchari 2-methylcitrate synthase PrpC SWALL:Q8VPS9 (EMBL:AY033092) (388 aa) fasta scores: E(): 1.2e-133, 86.15% id in 390 aa.
  
 0.957
gltA
Citrate synthase; Similar to Rhizobium meliloti citrate synthase GltA or r01509 or smc02087 SWALL:CISY_RHIME (SWALL:O33915) (429 aa) fasta scores: E(): 1.4e-128, 70.23% id in 430 aa, and to Ralstonia solanacearum probable citrate synthase protein rsc1991 or rs03559 SWALL:Q8XXX2 (EMBL:AL646067) (433 aa) fasta scores: E(): 6.9e-149, 82.44% id in 433 aa.
  
 0.957
acoD
Similar to Alcaligenes eutrophus acetaldehyde dehydrogenase II AcoD SWALL:DHA2_ALCEU (SWALL:P46368) (506 aa) fasta scores: E(): 5.2e-172, 81.02% id in 506 aa.
   
 0.954
aceB
Similar to Escherichia coli malate synthase A AceB or Mas or b4014 SWALL:MASY_ECOLI (SWALL:P08997) (533 aa) fasta scores: E(): 1.9e-103, 50.84% id in 533 aa, and to Ralstonia solanacearum probable malate synthase A rsc1363 or rs04645 SWALL:Q8XZN2 (EMBL:AL646064) (529 aa) fasta scores: E(): 1.5e-177, 79.84% id in 531 aa.
   
 0.953
BPSS1955
Putative phosphate acetyltransferase/enoyl-CoA hydratase fusion protein; N-terminal region similar to Pseudomonas aeruginosa (R)-specific enoyl-CoA hydratase PhaJ1 or pa3302 SWALL:Q9LBK2 (EMBL:AB040025) (156 aa) fasta scores: E(): 1.1e-17, 44.44% id in 153 aa, and C-terminal region to Rhizobium meliloti phosphate acetyltransferase Pta SWALL:PTA_RHIME (SWALL:Q9X448) (316 aa) fasta scores: E(): 5.4e-55, 57.37% id in 305 aa.
  
 
 0.948
BPSL1020
Similar to Escherichia coli putative aldehyde dehydrogenase AldH or b1300 SWALL:DHAL_ECOLI (SWALL:P23883) (495 aa) fasta scores: E(): 2.3e-61, 41.12% id in 479 aa, and to Ralstonia solanacearum probable aldehyde dehydrogenase oxidoreductase protein rsc2350 or rs01196 SWALL:Q8XWX0 (EMBL:AL646069) (478 aa) fasta scores: E(): 5.1e-138, 73.31% id in 476 aa.
   
 0.940
BPSS0514
acetyl-CoA hydrolase/transferase; Similar to Clostridium kluyveri succinyl-CoA:coenzyme A transferase Cat1 SWALL:CAT1_CLOKL (SWALL:P38946) (538 aa) fasta scores: E(): 2e-97, 51.73% id in 520 aa, and to Xanthomonas campestris coa tranferase xcc3588 SWALL:Q8P4W8 (EMBL:AE012479) (504 aa) fasta scores: E(): 1.2e-133, 68.52% id in 502 aa. Possible alternative translational start sites.
  
 0.940
BPSS1466
Putative aldehyde dehydrogenase family protein; Similar to Streptomyces clavuligerus semialdehyde dehydrogenase Pcd SWALL:O85725 (EMBL:AF073895) (512 aa) fasta scores: E(): 2e-120, 66.05% id in 492 aa, and to Ralstonia solanacearum putative transmembrane aldehyde dehydrogenase oxidoreductase protein rsp1591 or rs02148 SWALL:Q8XPP7 (EMBL:AL646085) (504 aa) fasta scores: E(): 9.4e-134, 69.84% id in 504 aa, and to Rhizobium loti aldehyde dehydrogenase mll2867 SWALL:Q98HH4 (EMBL:AP003000) (504 aa) fasta scores: E(): 4.1e-132, 68.93% id in 499 aa.
   
 0.940
ackA
Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.940
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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