STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSS0509Possible fusion protein. N-terminal region is similar to Mytilus edulis phosphoenolpyruvate phosphomutase SWALL:PEPM_MYTED (SWALL:P56839) (295 aa) fasta scores: E(): 1.1e-72, 68.18% id in 286 aa, and to Tetrahymena pyriformis phosphoenolpyruvate phosphomutase precursor pepM SWALL:PEPM_TETPY (SWALL:P33182) (300 aa) fasta scores: E(): 2.7e-68, 61.95% id in 297 aa. C-terminal region is weakly similar to Pseudomonas putida transferase, putative pp0726 SWALL:AAN66351 (EMBL:AE016776) (241 aa) fasta scores: E(): 4.1e-13, 28.76% id in 226 aa. (544 aa)    
Predicted Functional Partners:
BPSS0508
Putative thiamine pyrophosphate enzyme; Similar to Streptomyces viridochromogenes 3-phosphonopyruvate decarboxylase Ppd SWALL:O86938 (EMBL:Y14337) (397 aa) fasta scores: E(): 3.7e-49, 45.29% id in 393 aa, and to Streptomyces hygroscopicus 3-phosphonopyruvate decarboxylase BcpC SWALL:BAA07055 (EMBL:D37809) (401 aa) fasta scores: E(): 5.5e-46, 43.9% id in 394 aa.
 0.997
BPSS0609
Thiamine pyrophosphate enzyme family protein; Similar to Streptomyces wedmorensis phosphonopyruvate decarboxylase Fom2 SWALL:Q56190 (EMBL:AB016934) (384 aa) fasta scores: E(): 3.2e-56, 47.48% id in 377 aa, and to Streptomyces viridochromogenes 3-phosphonopyruvate decarboxylase Ppd SWALL:O86938 (EMBL:Y14337) (397 aa) fasta scores: E(): 8.5e-37, 38.51% id in 405 aa.
 0.982
phnW-2
Putative aminotransferase class-V; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
 
  
 0.949
BPSS0610
Similar to Tetrahymena pyriformis phosphoenolpyruvate phosphomutase precursor PepM SWALL:PEPM_TETPY (SWALL:P33182) (300 aa) fasta scores: E(): 5e-19, 32.05% id in 287 aa, and to he c-terminal region of Bacteroides fragilis putative phosphoenolpyruvate phosphomutase AepX SWALL:Q9F765 (EMBL:AF285774) (433 aa) fasta scores: E(): 1.7e-55, 52% id in 300 aa.
 
  
 
0.934
BPSS0510
Conserved hypothetical protein; Similar to Caulobacter crescentus nucleotidyltransferase family protein cc1152 SWALL:Q9A942 (EMBL:AE005793) (253 aa) fasta scores: E(): 3.8e-14, 32.93% id in 249 aa, and to Archaeoglobus fulgidus glucose-1-phosphate cytidylyltransferase af1142 SWALL:O29123 (EMBL:AE001025) (241 aa) fasta scores: E(): 3.2e-13, 28.62% id in 248 aa.
 
    0.916
selB
Similar to Escherichia coli selenocysteine-specific elongation factor SelB or FdhA or b3590 SWALL:SELB_ECOLI (SWALL:P14081) (614 aa) fasta scores: E(): 1.4e-43, 42.45% id in 636 aa, and to Pseudomonas aeruginosa selenocysteine-specific elongation factor SelB or pa4807 SWALL:Q9HV02 (EMBL:AE004893) (641 aa) fasta scores: E(): 5.8e-97, 49.76% id in 639 aa.
    
 0.897
BPSS0512
Hypothetical protein; Weakly similar to Streptomyces griseus ArpA protein SWALL:Q54223 (EMBL:X79605) (250 aa) fasta scores: E(): 8.3e-05, 26.02% id in 196 aa.
 
   0.891
BPSS0513
Putative CDP-alcohol phosphatidyltransferase; Weakly similar to Aeropyrum pernix hypothetical protein ape1516 SWALL:Q9YBT3 (EMBL:AP000061) (223 aa) fasta scores: E(): 2.3e-05, 27.91% id in 197 aa, and to Streptomyces coelicolor putative transmembrane protein SCO3457 or SCE46.14 SWALL:Q9RKH5 (EMBL:AL939116) (205 aa) fasta scores: E(): 0.00014, 32.63% id in 190 aa; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
   0.870
BPSS0511
Putative membrane protein; Similar to Pseudomonas aeruginosa hypothetical protein pa4313 SWALL:Q9HW88 (EMBL:AE004847) (333 aa) fasta scores: E(): 4.3e-05, 25.98% id in 304 aa, and to Mycobacterium leprae probable integral membrane protein ml2618 SWALL:Q9CD01 (EMBL:AL583926) (352 aa) fasta scores: E(): 0.12, 24.31% id in 329 aa.
 
   
 0.850
rmlC
dTDP-6-deoxy-D-glucose-3,5 epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
  
 0.735
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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