STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadXConserved hypothetical protein; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (271 aa)    
Predicted Functional Partners:
BPSS0898
Similar to Pseudomonas aeruginosa hypothetical protein pa3510 SWALL:Q9HY99 (EMBL:AE004771) (176 aa) fasta scores: E(): 5.9e-50, 71.25% id in 167 aa, and to Rhodococcus sp. hypothetical protein SWALL:BAC00796 (EMBL:AB070454) (171 aa) fasta scores: E(): 1.2e-24, 49.36% id in 158 aa.
 
     0.939
BPSS0902
Putative thiamine pyrophosphate enzyme; Similar to Pseudomonas aeruginosa probable decarboxylase pa3506 SWALL:Q9HYA3 (EMBL:AE004771) (560 aa) fasta scores: E(): 1.8e-134, 66.13% id in 561 aa. Weakly similar to Escherichia coli acetolactate synthase isozyme I large subunit IlvB SWALL:ILVB_ECOLI (SWALL:P08142) (562 aa) fasta scores: E(): 1.8e-32, 28.57% id in 532 aa; Belongs to the TPP enzyme family.
 
     0.935
BPSS0905
Glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein; C-terminal region is similar to Pseudomonas aeruginosa hypothetical protein pa3503 SWALL:Q9HYA6 (EMBL:AE004770) (211 aa) fasta scores: E(): 1.1e-60, 67.3% id in 208 aa. Full length CDS is weakly similar to Pseudomonas aeruginosa putative dioxygenase SWALL:O87625 (EMBL:AF087482) (309 aa) fasta scores: E(): 8.8e-13, 28.28% id in 297 aa. N-terminus is weakly similar to the N-terminal region of Rhodococcus rhodochrous metapyrocatechase CatA SWALL:CATA_RHORH (SWALL:Q53034) (318 aa) fasta scores: E(): 9.8e-05, 27.79% id [...]
 
    0.930
nadA
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.
    
 0.928
nadB
Putative L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
 0.914
BPSS0896
Rieske [2Fe-2S] domain protein; Similar to Pseudomonas sp. vanillate O-demethylase oxygenase subunit VanA SWALL:VANA_PSESP (SWALL:O05616) (354 aa) fasta scores: E(): 4e-18, 30.44% id in 358 aa, and to Acinetobacter sp. ADP1 hypothetical protein SWALL:O24847 (EMBL:AF009672) (316 aa) fasta scores: E(): 2.1e-88, 62.97% id in 316 aa.
 
    0.896
BPSS0901
Putative short chain dehydrogenase; Similar to Streptomyces cinnamonensis monensin polyketide synthase putative ketoacyl reductase SWALL:DHKR_STRCM (SWALL:P41177) (261 aa) fasta scores: E(): 8.2e-19, 34.88% id in 258 aa, and to Pseudomonas aeruginosa probable short-chain dehydrogenase pa3507 SWALL:Q9HYA2 (EMBL:AE004771) (265 aa) fasta scores: E(): 2.4e-60, 61.74% id in 264 aa.
 
     0.881
BPSS0899
Putative hydrolase; Similar to Pseudomonas aeruginosa probable hydrolase pa3509 SWALL:Q9HYA0 (EMBL:AE004771) (289 aa) fasta scores: E(): 6e-33, 44.76% id in 277 aa, and to Agrobacterium tumefaciens hydrolase ATU4238 or AGR_L_1247 SWALL:Q8U861 (EMBL:AE009353) (286 aa) fasta scores: E(): 1.9e-10, 29.89% id in 291 aa.
 
     0.879
BPSS0900
IclR family regulatory protein; Similar to Pseudomonas aeruginosa probable transcriptional regulator pa3508 SWALL:Q9HYA1 (EMBL:AE004771) (277 aa) fasta scores: E(): 6.5e-43, 49.62% id in 268 aa, and weakly similar to Pseudomonas putida Pca regulon regulatory protein PcaR SWALL:PCAR_PSEPU (SWALL:Q52154) (291 aa) fasta scores: E(): 1.4e-12, 26.37% id in 254 aa. Similar to BPSS0892, 64.184% identity (65.108% ungapped) in 282 aa overlap.
 
    0.848
pyrB-2
Similar to Burkholderia cepacia aspartate transcarbamoylase PyrB SWALL:Q9F9H3 (EMBL:AF192346) (431 aa) fasta scores: E(): 1.6e-157, 92.82% id in 432 aa, and to Pisum sativum aspartate carbamoyltransferase 2, chloroplast precursor PyrB2 SWALL:PYB2_PEA (SWALL:Q43087) (385 aa) fasta scores: E(): 2e-42, 43.61% id in 321 aa, and to Pisum sativum aspartate carbamoyltransferase 3, chloroplast precursor PyrB3 SWALL:PYB3_PEA (SWALL:Q43064) (391 aa) fasta scores: E(): 2.3e-42, 42.94% id in 333 aa; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
  
  
  0.827
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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