STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSS0933Similar to Escherichia coli methyl-accepting chemotaxis protein I Tsr or CheD SWALL:MCP1_ECOLI (SWALL:P02942) (551 aa) fasta scores: E(): 4.2e-61, 44.29% id in 526 aa, and to Ralstonia solanacearum probable methyl-accepting chemotaxis transmembrane protein rsp0303 or rs05471 SWALL:Q8XT14 (EMBL:AL646077) (515 aa) fasta scores: E(): 1.3e-76, 50.78% id in 512 aa. CDS is truncated at the C-terminus in comparison to some orthologues. Similar to N-terminal region of BPSL1829, 51.908% identity (52.510% ungapped) in 524 aa overlap. (518 aa)    
Predicted Functional Partners:
cheR
Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 0.984
cheB
Chemotaxis protein-glutamate methylesterase protein CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.982
cheA
Chemotaxis two-component sensor kinase CheA; Similar to Escherichia coli chemotaxis protein CheA or b1888 SWALL:CHEA_ECOLI (SWALL:P07363) (654 aa) fasta scores: E(): 9.5e-76, 56.14% id in 741 aa.
 
 0.980
cheD
Putative chemotaxis protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  0.978
cheW2
Chemotaxis protein CheW2; Similar to Escherichia coli, and Escherichia coli O157:H7 chemotaxis protein CheW or b1887 or z2941 or ecs2597 SWALL:CHEW_ECOLI (SWALL:P07365) (167 aa) fasta scores: E(): 4.1e-30, 59.86% id in 147 aa, and to Burkholderia pseudomallei chemotaxis protein CheW SWALL:O05183 (EMBL:U92493) (175 aa) fasta scores: E(): 9.4e-32, 57.31% id in 164 aa. Note: Also similar to BPSL3305 cheW (176 aa) fasta scores: E(): 9.3e-31, 60.131% identity in 153 aa overlap.
 
 0.973
cheW
Chemotaxis protein CheW; Previously characterised as Burkholderia pseudomallei chemotaxis protein CheW SWALL:O05183 (EMBL:U92493) (175 aa) fasta scores: E(): 2.1e-66, 100% id in 175 aa, and to Escherichia coli chemotaxis protein CheW or b1887 or z2941 or ecs2597 SWALL:CHEW_ECOLI (SWALL:P07365) (167 aa) fasta scores: E(): 9.8e-39, 71.81% id in 149 aa.
 
 0.973
BPSS1871
Putative chemotaxis-related histidine kinase protein; Similar to Thermotoga maritima chemotaxis protein CheA or tm0702 SWALL:CHEA_THEMA (SWALL:Q56310) (671 aa) fasta scores: E(): 2.2e-33, 27.4% id in 708 aa, and to Rhizobium loti chemotaxis histidine kinase mll9511 SWALL:Q98PD0 (EMBL:AP003017) (757 aa) fasta scores: E(): 1.1e-104, 49.07% id in 864 aa.
 
 
 0.919
cheY1
Chemotaxis two-component response regulator CheY1; Similar to Rhizobium meliloti chemotaxis regulator CheY or R00638 or Smc03006 SWALL:Q52879 (EMBL:U13166) (121 aa) fasta scores: E(): 7.1e-15, 43.8% id in 121 aa.
  
  0.896
BPSS1873
Similar to Ralstonia solanacearum putative methyltransferase protein rsp1647 or rs02206 SWALL:Q8XPJ3 (EMBL:AL646086) (466 aa) fasta scores: E(): 1.3e-45, 37.71% id in 684 aa, and to Myxococcus xanthus protein methyltransferase FrzF SWALL:FRZF_MYXXA (SWALL:P31759) (593 aa) fasta scores: E(): 7.1e-08, 27.28% id in 546 aa.
 
 
 0.821
cheB2
Putative chemotaxis-related methylesterase protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.820
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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