STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSS1374Putative glutathione-S-transferase; Similar to Ralstonia solanacearum probable glutathione S-transferase protein rsc3070 or rs00514 SWALL:Q8XUW3 (EMBL:AL646073) (238 aa) fasta scores: E(): 4.1e-53, 59.75% id in 241 aa, and to Rhizobium meliloti probable glutathione S-transferase protein Gst12 or rb1278 or smb21449 SWALL:Q92U61 (EMBL:AL603646) (240 aa) fasta scores: E(): 1.1e-49, 56.19% id in 242 aa, and to Xanthomonas axonopodis glutathione transferase xac3203 SWALL:AAM38047 (EMBL:AE011966) (241 aa) fasta scores: E(): 1.2e-48, 56.96% id in 244 aa. (242 aa)    
Predicted Functional Partners:
BPSL0264
Conserved hypothetical protein; Similar to Pseudomonas pseudoalcaligenes glutathione S-transferase BphX0 SWALL:Q52037 (EMBL:D85853) (203 aa) fasta scores: E(): 7.5e-05, 30.8% id in 198 aa, and to Ralstonia solanacearum hypothetical protein rsc0086 or rs02260 SWALL:Q8Y394 (EMBL:AL646057) (229 aa) fasta scores: E(): 7.5e-42, 57% id in 207 aa.
 
  
  0.918
BPSS2048
Similar to Caulobacter crescentus glutathione S-transferase family protein Cc2647 SWALL:Q9A522 (EMBL:AE005932) (215 aa) fasta scores: E(): 6.4e-51, 57.94% id in 214 aa, and to Zea mays glutathione S-transferase III Gst3 SWALL:GTH3_MAIZE (SWALL:P04907) (221 aa) fasta scores: E(): 8e-11, 29.66% id in 209 aa.
  
  
  0.916
BPSL1238
Putative glutathione S-transferase related protein; Similar to Ralstonia solanacearum probable GST-related protein rsc2012 or rs03580 SWALL:Q8XXV1 (EMBL:AL646067) (218 aa) fasta scores: E(): 7.8e-36, 50.71% id in 209 aa, and to Arabidopsis thaliana glutathione S-transferase 6 Gst6 or at2g47730 or f17a22.12 SWALL:GTH6_ARATH (SWALL:Q96266) (215 aa) fasta scores: E(): 3.3e-07, 27.67% id in 224 aa.
     
 0.910
gpo
Glutathione peroxidase; Full length similarity to Saccharomyces cerevisiae glutathione peroxidase Hyr1 SWALL:GSHJ_YEAST (SWALL:P40581) (163 aa) fasta scores: E(): 1.2e-33, 50.94% id in 159 aa, and to Synechocystis sp. putative glutathione peroxidase slr1171 SWALL:GPO_SYNY3 (SWALL:P74250) (169 aa) fasta scores: E(): 4.3e-40, 62.11% id in 161 aa.
   
 
 0.910
BPSL2891
Putative glutathione S-transferase-related protein; Similar to Escherichia coli, and Escherichia coli O6 hypothetical GST-like protein YibF or b3592 or c4413 SWALL:YIBF_ECOLI (SWALL:P32105) (202 aa) fasta scores: E(): 4.1e-20, 35.82% id in 201 aa, and to Ralstonia solanacearum putative glutathione S-transferase protein rsc2721 or rs00001 SWALL:Q8XVV6 (EMBL:AL646071) (202 aa) fasta scores: E(): 1.2e-58, 66.33% id in 202 aa.
     
 0.908
BPSS0640
Similar to Zea mays glutathione S-transferase III Gst3 SWALL:GTH3_MAIZE (SWALL:P04907) (221 aa) fasta scores: E(): 2e-05, 30.18% id in 212 aa, and to Rhizobium meliloti putative glutathione S-transferase protein r02060 or smc04321 SWALL:Q92NV7 (EMBL:AL591789) (224 aa) fasta scores: E(): 1.3e-36, 48.59% id in 214 aa.
     
 0.908
gshB
Similar to Escherichia coli glutathione synthetase GshB or Gsh-II SWALL:GSHB_ECOLI (SWALL:P04425) (316 aa) fasta scores: E(): 3.4e-53, 48.22% id in 309 aa, and to Ralstonia solanacearum glutathione synthetase rsc0345 or rs03312 SWALL:GSHB_RALSO (SWALL:P58579) (324 aa) fasta scores: E(): 2.8e-80, 68.43% id in 320 aa; Belongs to the prokaryotic GSH synthase family.
    
 0.906
gor
Glutathione reductase; Maintains high levels of reduced glutathione.
    
 0.905
BPSL3019
Putative redoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 
 0.902
BPSL0671
Conserved hypothetical protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
  0.900
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.