STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSS1494Putative two-component response regulator protein; Similar to Rhizobium sp LcrB protein SWALL:Q53167 (EMBL:M38698) (238 aa) fasta scores: E(): 9.9e-34, 43.16% id in 234 aa, and to Agrobacterium tumefaciens Tiorf152 protein SWALL:BAA87777 (EMBL:AB016260) (253 aa) fasta scores: E(): 3.5e-32, 41% id in 239 aa, and to Agrobacterium tumefaciens regulatory protein VirG or atu6178 or agr_pti_15 SWALL:VIRG_AGRT5 (SWALL:P07545) (253 aa) fasta scores: E(): 3.5e-32, 41% id in 239 aa. (245 aa)    
Predicted Functional Partners:
BPSS1495
Putative two-component regulator sensor kinase; Similar to Pseudomonas aeruginosa probable two-component sensor pa2571 SWALL:Q9I0R5 (EMBL:AE004685) (470 aa) fasta scores: E(): 4.9e-11, 26.43% id in 401 aa, and to Chlorobium tepidum sensor histidine kinase/response regulator ct1396 SWALL:AAM72624 (EMBL:AE012897) (808 aa) fasta scores: E(): 2.1e-06, 29.09% id in 409 aa, and to Anabaena sp. two-component hybrid sensor and regulator alr1968 SWALL:Q8YVK7 (EMBL:AP003587) (759 aa) fasta scores: E(): 2.3e-06, 29.8% id in 312 aa.
 
 
 0.959
BPSS2246
Putative sensor kinase/response regulator fusion protein; Similar to Anabaena sp. two-component hybrid sensor and regulator alr3442 SWALL:Q8YRK4 (EMBL:AP003593) (865 aa) fasta scores: E(): 1.3e-49, 30.58% id in 680 aa, and to Ralstonia solanacearum probable composite two-component regulatory rsp1676 or rs02235 SWALL:Q8XPG5 (EMBL:AL646086) (796 aa) fasta scores: E(): 1e-42, 32.65% id in 640 aa.
 
 
 0.943
BPSL2025
Putative two component regulatory system, sensor kinase; Similar to the C-terminal region of Escherichia coli sensor protein RcsC or b2218 SWALL:RCSC_ECOLI (SWALL:P14376) (949 aa) fasta scores: E(): 2e-37, 32.94% id in 513 aa, and of Salmonella typhi sensor protein RcsC or sty2496 SWALL:RCSC_SALTI (SWALL:Q56128) (948 aa) fasta scores: E(): 1.2e-35, 32.82% id in 521 aa.
 
 
 0.929
BPSS1940
Similar to Caulobacter crescentus sensory box histidine kinase/response regulator cc3225 SWALL:Q9A3H9 (EMBL:AE005986) (731 aa) fasta scores: E(): 9.5e-57, 35.17% id in 688 aa, and to Pseudomonas putida sensor histidine kinase/response regulator pp3651 SWALL:AAN69251 (EMBL:AE016787) (727 aa) fasta scores: E(): 6.1e-51, 33.19% id in 729 aa.
 
 
 0.893
BPSS1876
Putative sensor kinase/response regulator fusion protein; N-terminal region similar to Pseudomonas aeruginosa probable two-component response regulator pa3702 SWALL:Q9HXT9 (EMBL:AE004789) (347 aa) fasta scores: E(): 3.7e-29, 64.92% id in 134 aa, C-terminal region to Caulobacter crescentus sensory box histidine kinase, putative cc3327 SWALL:Q9A377 (EMBL:AE005994) (761 aa) fasta scores: E(): 9.5e-22, 37.61% id in 226 aa, and in full length to Mycobacterium leprae sensor-like histidine kinase SenX3 or ml2440 or b2168_c3_247 SWALL:SEX3_MYCLE (SWALL:P54883) (443 aa) fasta scores: E(): 1.9e- [...]
 
 
 0.828
irlS2
Metal-related two-component system, histidine kinase; Member of a two-component regulatory system.
 
 0.814
BPSS0642
Similar to Escherichia coli sensor protein QseC SWALL:QSEC_ECOLI (SWALL:P40719) (449 aa) fasta scores: E(): 4.6e-27, 32.08% id in 452 aa, and to Ralstonia solanacearum probable transmembrane two-component sensor kinase transcription regulator protein rsp1553 or rs02109 SWALL:Q8XPT4 (EMBL:AL646085) (438 aa) fasta scores: E(): 9.4e-50, 41.34% id in 445 aa.
 
 
 0.804
BPSS0687
Similar to Escherichia coli sensor protein RstB or UspT SWALL:RSTB_ECOLI (SWALL:P18392) (433 aa) fasta scores: E(): 3.3e-37, 33.63% id in 437 aa, and to Ralstonia solanacearum probable transmembrane sensor histidine kinase transcription regulator protein rsc3063 or rs00507 SWALL:Q8XUX0 (EMBL:AL646073) (433 aa) fasta scores: E(): 1.9e-84, 55.88% id in 433 aa.
 
 
 0.803
irlS
Putative transmembrane invasion-related two-component sensor protein; Member of the two-component regulatory system IrlR/IrlS. May be involved in invasion of eukaryotic cells and heavy-metal resistance. Probably activates IrlR by phosphorylation (By similarity).
 
 0.802
BPSS1605
Probable two-component system sensor kinase; Similar to Deinococcus radiodurans sensor histidine kinase dr1606 SWALL:Q9RTZ2 (EMBL:AE002004) (433 aa) fasta scores: E(): 4.8e-10, 30.22% id in 354 aa.
  
 
 0.800
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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