STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
deoAThymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (440 aa)    
Predicted Functional Partners:
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
 
 0.992
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
 
 0.987
codA
Similar to Escherichia coli cytosine deaminase CodA SWALL:CODA_ECOLI (SWALL:P25524) (426 aa) fasta scores: E(): 8.3e-86, 56.02% id in 407 aa, and to Salmonella typhimurium putative cytosine deaminase stm3334 SWALL:Q8ZLR0 (EMBL:AE008853) (426 aa) fasta scores: E(): 3.6e-88, 56.71% id in 402 aa.
 
  
 0.972
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.
 
 
 0.971
surE
Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.969
pyrR
Bifunctional regulator/uracil phosphoribosyltransferase; Similar to Bacillus caldolyticus PyrR bifunctional protein [includes: pyrimidine operon regulatory protein; uracil phosphoribosyltransferase] SWALL:PYRR_BACCL (SWALL:P41007) (179 aa) fasta scores: E(): 2.1e-14, 41.61% id in 161 aa, and to Pseudomonas aeruginosa PyrR bifunctional protein [includes: pyrimidine operon regulatory protein; uracil phosphoribosyltransferase pyrr or pa0403 SWALL:Q9X6W6 (EMBL:AF148692) (170 aa) fasta scores: E(): 2.7e-21, 47.02% id in 151 aa.
     
 0.964
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
    0.698
CodB
Similar to Escherichia coli cytosine permease CodB SWALL:CODB_ECOLI (SWALL:P25525) (419 aa) fasta scores: E(): 5.7e-44, 32.85% id in 414 aa, and to Pseudomonas aeruginosa cytosine permease pa0438 SWALL:Q9I679 (EMBL:AE004481) (416 aa) fasta scores: E(): 2.8e-44, 33.01% id in 415 aa.
      
 0.690
BPSS1106
Putative thymidylate synthase protein; Similar to Bacteriophage SP01 deoxyuridylate hydroxymethyltransferase 29 SWALL:DUHM_BPSP1 (SWALL:P31654) (383 aa) fasta scores: E(): 6.8e-12, 30.04% id in 223 aa, and to Rhizobium loti thymidylate synthase ThyA or mll1467 SWALL:Q98KH9 (EMBL:AP002997) (264 aa) fasta scores: E(): 8e-08, 24.05% id in 237 aa, and to Agrobacterium tumefaciens thymidylate synthase ThyA or atu2047 or agr_c_3709 SWALL:Q8UDS3 (EMBL:AE009155) (279 aa) fasta scores: E(): 6.8e-07, 23.72% id in 236 aa.
     
 0.626
BPSL0463
Probable lipoprotein; Similar to Ralstonia solanacearum probable lipoprotein rsc0373 or rs03341 SWALL:Q8Y2G3 (EMBL:AL646058) (200 aa) fasta scores: E(): 5.3e-49, 64.76% id in 193 aa> Internal region is similar to Homo sapiens mitochondrial, cytochrome c oxidase subunit II processing protein SCO2 SWALL:SCO2_HUMAN (SWALL:O43819) (266 aa) fasta scores: E(): 8e-17, 35.67% id in 171 aa.
 
 
    0.622
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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