STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MtlAPTS system, mannitol-specific IIBC component (gene MtlA); The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport. (481 aa)    
Predicted Functional Partners:
MltF
PTS system, mannitol-specific IIA domain (Ntr-type) (gene MltF).
 
 0.999
MtlD
Possible sigma factor, diverged member of sigF/sigE/sigG family.
 
 
 0.999
MtlR
Putative regulator of the PTS system for mannitol (gene MltR).
 
  
 0.998
CA_C1820
Phosphocarrier Protein (Hpr).
   
 0.957
uxaB
Altronate oxidoreductase; Belongs to the mannitol dehydrogenase family. UxaB subfamily.
 
  
 0.751
CA_C0149
Hypothetical protein.
   
    0.730
CA_C1454
Membrane associated histidine kinase-like ATPase.
   
    0.704
CA_C2729
Secreted protein containing SH3 domain homolog.
   
    0.656
CA_C3088
NtrC family transcriptional regulator, ATPase domain fused to two PAS domains.
   
 
 0.587
lacE
PTS system lactose-specific enzyme IIBC.
  
  
 0.548
Your Current Organism:
Clostridium acetobutylicum
NCBI taxonomy Id: 272562
Other names: C. acetobutylicum ATCC 824, Clostridium acetobutylicum ATCC 824, Clostridium acetobutylicum DSM 792, Clostridium acetobutylicum str. ATCC 824, Clostridium acetobutylicum strain ATCC 824
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