STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
fabVProtein of short-chain alcohol dehydrogenase family; Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of the carbon-carbon double bond of crotonyl-CoA to yield butyryl-CoA. (398 aa)    
Predicted Functional Partners:
bcd
Butyryl-CoA dehydrogenase; Belongs to the acyl-CoA dehydrogenase family.
    
 0.951
fabZ
Hydroxymyristoyl-(acyl carrier protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
 
 0.940
pksF
3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 
 0.927
crt
Crotonase (3-hydroxybutyryl-COA dehydratase); Catalyzes the reversible hydration of crotonyl-CoA. Can also use hexenoyl-CoA but not higher analogs.
   
 
 0.927
fabF
3-oxoacyl-(acyl-carrier-protein) synthase I; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.927
ptb
Phosphate butyryltransferase; Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate.
   
 
  0.900
CA_C3576
Dioxygenase related to 2-nitropropane dioxygenase.
     
  0.900
CA_C0460
CBS-domain containing protein, YHDP B.subtilis ortholog.
  
  
 0.879
CA_C0461
Mercuric resistance operon regulatory protein, MerR family.
  
    0.757
CA_C0271
Predicted esterase.
      
 0.644
Your Current Organism:
Clostridium acetobutylicum
NCBI taxonomy Id: 272562
Other names: C. acetobutylicum ATCC 824, Clostridium acetobutylicum ATCC 824, Clostridium acetobutylicum DSM 792, Clostridium acetobutylicum str. ATCC 824, Clostridium acetobutylicum strain ATCC 824
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