STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
splB-2Spore photoproduct lyase, splB; Involved in repair of UV radiation-induced DNA damage during spore germination. Can repair thymine dimer 5-thyminyl-5,6- dihydrothymine (known as spore photoproduct (SP)) by in situ monomerization of SP to two thymines. (336 aa)    
Predicted Functional Partners:
CA_C0477
AP superfamily.
      
 0.725
nrdD-2
Anaerobic ribonucleotide reductase.
      
 0.725
nfi
Deoxyinosine 3'endonuclease; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
      
 0.724
moaA
Molybdenum cofactor biosynthesis enzyme MoaA, Fe-S oxidoreductase; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
      
 0.706
asnS
Aspartyl/asparaginyl-tRNA synthetase.
      
 0.683
lexA
P-loop ATPase domain fused to LexA-like protein; Belongs to the peptidase S24 family.
  
  
 0.624
CA_C0130
Uncharacterized membrane protein, YTAF B.subtilis ortholog; Probably functions as a manganese efflux pump.
  
     0.617
CA_C0325
Uncharacterized membrane protein, homolog of YtaF B.subtilis; Probably functions as a manganese efflux pump.
  
     0.608
CA_C0698
Predicted hydrolase of the HAD superfamily.
  
    0.602
cspR
Predicted tRNA-methylase (SpoU class); Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.566
Your Current Organism:
Clostridium acetobutylicum
NCBI taxonomy Id: 272562
Other names: C. acetobutylicum ATCC 824, Clostridium acetobutylicum ATCC 824, Clostridium acetobutylicum DSM 792, Clostridium acetobutylicum str. ATCC 824, Clostridium acetobutylicum strain ATCC 824
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