node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CA_C2306 | SpoIIP | CA_C2306 | CA_C1276 | Sporulation-specific sigma factor F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein P. | 0.693 |
CA_C2306 | SpoVAC | CA_C2306 | CA_C2305 | Sporulation-specific sigma factor F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage V sporulation AC, SpoVAC. | 0.889 |
CA_C2306 | sigG | CA_C2306 | CA_C1696 | Sporulation-specific sigma factor F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Specialized DNA-dependent RNA polymerase sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. | 0.516 |
CA_C2306 | spo0A | CA_C2306 | CA_C2071 | Sporulation-specific sigma factor F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Spo0A protein, (CheY-like receiver domain and HTH-type DNA binding domain); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process (By similarity). | 0.824 |
CA_C2306 | spoIIAA | CA_C2306 | CA_C2308 | Sporulation-specific sigma factor F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-anti-sigma factor (antagonist of SpoIIAB); Belongs to the anti-sigma-factor antagonist family. | 0.960 |
CA_C2306 | spoIIAB | CA_C2306 | CA_C2307 | Sporulation-specific sigma factor F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Sigma factor F inhibitor spoIIAB (anti-sigma factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.987 |
CA_C2306 | spoIIE | CA_C2306 | CA_C3205 | Sporulation-specific sigma factor F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein E, serine phosphatase family. | 0.801 |
CA_C2306 | spoIIGA | CA_C2306 | CA_C1694 | Sporulation-specific sigma factor F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Sigma factor E processing enzyme, SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR (By similarity). Belongs to the peptidase U4 family. | 0.780 |
CA_C2306 | spoIIID | CA_C2306 | CA_C2859 | Sporulation-specific sigma factor F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage III sporulation protein D, SpoIIID. | 0.749 |
CA_C2306 | spoIIR | CA_C2306 | CA_C2898 | Sporulation-specific sigma factor F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein R. | 0.700 |
SpoIIP | CA_C2306 | CA_C1276 | CA_C2306 | Stage II sporulation protein P. | Sporulation-specific sigma factor F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.693 |
SpoIIP | SpoVAC | CA_C1276 | CA_C2305 | Stage II sporulation protein P. | Stage V sporulation AC, SpoVAC. | 0.796 |
SpoIIP | sigG | CA_C1276 | CA_C1696 | Stage II sporulation protein P. | Specialized DNA-dependent RNA polymerase sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. | 0.759 |
SpoIIP | spo0A | CA_C1276 | CA_C2071 | Stage II sporulation protein P. | Spo0A protein, (CheY-like receiver domain and HTH-type DNA binding domain); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process (By similarity). | 0.887 |
SpoIIP | spoIIAA | CA_C1276 | CA_C2308 | Stage II sporulation protein P. | Anti-anti-sigma factor (antagonist of SpoIIAB); Belongs to the anti-sigma-factor antagonist family. | 0.850 |
SpoIIP | spoIIAB | CA_C1276 | CA_C2307 | Stage II sporulation protein P. | Sigma factor F inhibitor spoIIAB (anti-sigma factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.958 |
SpoIIP | spoIIE | CA_C1276 | CA_C3205 | Stage II sporulation protein P. | Stage II sporulation protein E, serine phosphatase family. | 0.959 |
SpoIIP | spoIIGA | CA_C1276 | CA_C1694 | Stage II sporulation protein P. | Sigma factor E processing enzyme, SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR (By similarity). Belongs to the peptidase U4 family. | 0.937 |
SpoIIP | spoIIID | CA_C1276 | CA_C2859 | Stage II sporulation protein P. | Stage III sporulation protein D, SpoIIID. | 0.953 |
SpoIIP | spoIIR | CA_C1276 | CA_C2898 | Stage II sporulation protein P. | Stage II sporulation protein R. | 0.961 |