STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hbdBeta-hydroxybutyryl-CoA dehydrogenase, NAD-dependent; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (282 aa)    
Predicted Functional Partners:
crt
Crotonase (3-hydroxybutyryl-COA dehydratase); Catalyzes the reversible hydration of crotonyl-CoA. Can also use hexenoyl-CoA but not higher analogs.
 0.999
thlA
Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 0.999
fadB-2
Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.994
bcd
Butyryl-CoA dehydrogenase; Belongs to the acyl-CoA dehydrogenase family.
 
 0.994
fadB
Enoyl-CoA hydratase.
 
 0.992
etfB-2
Electron transfer flavoprotein beta-subunit; The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
  
 
 0.957
etfA-2
Electron transfer flavoprotein alpha-subunit; The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
  
 
 0.935
etfB
Electron-transferring flavoprotein small subunit.
  
 
 0.888
rex
AT-rich DNA-binding protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
  
 0.874
etfA
Electron-transferring flavoprotein large subunit.
  
 
 0.861
Your Current Organism:
Clostridium acetobutylicum
NCBI taxonomy Id: 272562
Other names: C. acetobutylicum ATCC 824, Clostridium acetobutylicum ATCC 824, Clostridium acetobutylicum DSM 792, Clostridium acetobutylicum str. ATCC 824, Clostridium acetobutylicum strain ATCC 824
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