node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CA_C0368 | gabT | CA_C0368 | CA_C1427 | 4 animobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 4-aminobutyrate aminotransferase (PLP-dependent); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.908 |
CA_C0368 | panC | CA_C0368 | CA_C2915 | 4 animobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.906 |
CA_C0368 | panD | CA_C0368 | CA_C2916 | 4 animobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.911 |
CA_C1720 | coaX | CA_C1720 | CA_C3200 | Flavoprotein involved in panthothenate metabolism, YLOI B.subtilis ortholog; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Predicted transcriptional regulator, homolog of Bvg accessory factor; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.946 |
CA_C1720 | panB | CA_C1720 | CA_C2914 | Flavoprotein involved in panthothenate metabolism, YLOI B.subtilis ortholog; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.543 |
CA_C1720 | panC | CA_C1720 | CA_C2915 | Flavoprotein involved in panthothenate metabolism, YLOI B.subtilis ortholog; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.905 |
CA_C1720 | panD | CA_C1720 | CA_C2916 | Flavoprotein involved in panthothenate metabolism, YLOI B.subtilis ortholog; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.415 |
CA_C2937 | panB | CA_C2937 | CA_C2914 | Ketopantoate reductase PanE/ApbA; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.986 |
CA_C2937 | panC | CA_C2937 | CA_C2915 | Ketopantoate reductase PanE/ApbA; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.944 |
bioD | panB | CA_C1361 | CA_C2914 | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.756 |
bioD | panC | CA_C1361 | CA_C2915 | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.820 |
bioD | panD | CA_C1361 | CA_C2916 | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.791 |
cmk | panC | CA_C1848 | CA_C2915 | Cytidylate kinase. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.906 |
coaX | CA_C1720 | CA_C3200 | CA_C1720 | Predicted transcriptional regulator, homolog of Bvg accessory factor; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | Flavoprotein involved in panthothenate metabolism, YLOI B.subtilis ortholog; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.946 |
coaX | panC | CA_C3200 | CA_C2915 | Predicted transcriptional regulator, homolog of Bvg accessory factor; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.968 |
coaX | panD | CA_C3200 | CA_C2916 | Predicted transcriptional regulator, homolog of Bvg accessory factor; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.722 |
gabT | CA_C0368 | CA_C1427 | CA_C0368 | 4-aminobutyrate aminotransferase (PLP-dependent); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 4 animobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.908 |
gabT | panC | CA_C1427 | CA_C2915 | 4-aminobutyrate aminotransferase (PLP-dependent); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.904 |
gabT | panD | CA_C1427 | CA_C2916 | 4-aminobutyrate aminotransferase (PLP-dependent); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.912 |
panB | CA_C1720 | CA_C2914 | CA_C1720 | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Flavoprotein involved in panthothenate metabolism, YLOI B.subtilis ortholog; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.543 |