node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CA_C0102 | CA_C0291 | CA_C0102 | CA_C0291 | O-acetylhomoserine sulfhydrylase. | FUSION: methionine sintase I (cobalamin dependent) and 5,10 methylenetetrahydrofolate reductase. | 0.946 |
CA_C0102 | CA_C0390 | CA_C0102 | CA_C0390 | O-acetylhomoserine sulfhydrylase. | Cystathionine gamma-synthase. | 0.928 |
CA_C0102 | CA_C0391 | CA_C0102 | CA_C0391 | O-acetylhomoserine sulfhydrylase. | Cystathionine beta-lyase. | 0.933 |
CA_C0102 | MmuM | CA_C0102 | CA_C3348 | O-acetylhomoserine sulfhydrylase. | Possible homocysteine S-methyltransferase. | 0.908 |
CA_C0102 | PatB | CA_C0102 | CA_C2970 | O-acetylhomoserine sulfhydrylase. | PLP-dependent aminotransferase. | 0.916 |
CA_C0102 | cysD-2 | CA_C0102 | CA_C2783 | O-acetylhomoserine sulfhydrylase. | O-acetylhomoserine sulfhydrylase. | 0.908 |
CA_C0102 | luxS | CA_C0102 | CA_C2942 | O-acetylhomoserine sulfhydrylase. | Uncharacterized conserved protein fron YGAG family, predicted metal-dependent enzyme; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD) (By similarity); Belongs to the LuxS family. | 0.906 |
CA_C0102 | metB | CA_C0102 | CA_C0930 | O-acetylhomoserine sulfhydrylase. | Cystathionine gamma-synthase. | 0.931 |
CA_C0102 | metH | CA_C0102 | CA_C0578 | O-acetylhomoserine sulfhydrylase. | Cobalamine-dependent methionine synthase I (methyltransferase and cobalamine-binding domain); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.950 |
CA_C0291 | CA_C0102 | CA_C0291 | CA_C0102 | FUSION: methionine sintase I (cobalamin dependent) and 5,10 methylenetetrahydrofolate reductase. | O-acetylhomoserine sulfhydrylase. | 0.946 |
CA_C0291 | CA_C0390 | CA_C0291 | CA_C0390 | FUSION: methionine sintase I (cobalamin dependent) and 5,10 methylenetetrahydrofolate reductase. | Cystathionine gamma-synthase. | 0.993 |
CA_C0291 | CA_C0391 | CA_C0291 | CA_C0391 | FUSION: methionine sintase I (cobalamin dependent) and 5,10 methylenetetrahydrofolate reductase. | Cystathionine beta-lyase. | 0.993 |
CA_C0291 | MmuM | CA_C0291 | CA_C3348 | FUSION: methionine sintase I (cobalamin dependent) and 5,10 methylenetetrahydrofolate reductase. | Possible homocysteine S-methyltransferase. | 0.953 |
CA_C0291 | PatB | CA_C0291 | CA_C2970 | FUSION: methionine sintase I (cobalamin dependent) and 5,10 methylenetetrahydrofolate reductase. | PLP-dependent aminotransferase. | 0.928 |
CA_C0291 | cysD-2 | CA_C0291 | CA_C2783 | FUSION: methionine sintase I (cobalamin dependent) and 5,10 methylenetetrahydrofolate reductase. | O-acetylhomoserine sulfhydrylase. | 0.946 |
CA_C0291 | luxS | CA_C0291 | CA_C2942 | FUSION: methionine sintase I (cobalamin dependent) and 5,10 methylenetetrahydrofolate reductase. | Uncharacterized conserved protein fron YGAG family, predicted metal-dependent enzyme; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD) (By similarity); Belongs to the LuxS family. | 0.965 |
CA_C0291 | metB | CA_C0291 | CA_C0930 | FUSION: methionine sintase I (cobalamin dependent) and 5,10 methylenetetrahydrofolate reductase. | Cystathionine gamma-synthase. | 0.993 |
CA_C0291 | metH | CA_C0291 | CA_C0578 | FUSION: methionine sintase I (cobalamin dependent) and 5,10 methylenetetrahydrofolate reductase. | Cobalamine-dependent methionine synthase I (methyltransferase and cobalamine-binding domain); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |
CA_C0291 | pfs | CA_C0291 | CA_C2117 | FUSION: methionine sintase I (cobalamin dependent) and 5,10 methylenetetrahydrofolate reductase. | Nucleoside phosphorylase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.463 |
CA_C0390 | CA_C0102 | CA_C0390 | CA_C0102 | Cystathionine gamma-synthase. | O-acetylhomoserine sulfhydrylase. | 0.928 |