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folA1 protein (Haloarcula marismortui) - STRING interaction network
"folA1" - Dihydrofolate reductase in Haloarcula marismortui
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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folA1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) (185 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (415 aa)
 
  0.951
purH
Bifunctional purine biosynthesis protein PurH (526 aa)
     
  0.937
gcvT4
Glycine cleavage system protein T (361 aa)
   
 
  0.912
gcvT
Probable aminomethyltransferase (EC-2.1.2.10); The glycine cleavage system catalyzes the degradation of glycine (363 aa)
   
 
  0.912
thyX
Thymidylate synthase; Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (247 aa)
   
 
  0.911
purU
Formyltetrahydrofolate deformylase (277 aa)
         
    0.900
rrnAC0858
Arylsulfatase (450 aa)
              0.859
folP
Dihydropteroate synthase (814 aa)
   
 
  0.835
rrnAC0857
tRNA 2’-O-methylase; Specifically catalyzes the AdoMet-dependent 2’-O-ribose methylation of cytidine at position 56 in tRNAs (180 aa)
              0.676
rrnAC0856
Hypothetical protein (222 aa)
              0.676
Your Current Organism:
Haloarcula marismortui
NCBI taxonomy Id: 272569
Other names: Flavobacterium (Halobacterium) maris-mortui, H. marismortui, H. marismortui ATCC 43049, Haloarcula marismortui, Haloarcula marismortui ATCC 43049, Haloarcula marismortui marismortui, Haloarcula marismortui str. ATCC 43049, Haloarcula marismortui strain ATCC 43049, Haloarcula marismortui subsp. marismortui, Halobacterium marismortui
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