STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (362 aa)    
Predicted Functional Partners:
hemL
Glutamate-1-semialdehyde 21-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
 
 0.995
hemC
Porphobilinogen deaminase.
  
 0.974
gltX
glutaminyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
     
 0.915
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.877
cysG1
uroporphyrin-III C-methyltransferase.
 
  
 0.819
cad
Pterin-4-alpha-carbinolamine dehydratase.
  
    0.807
hemX
uroporphyrin-III C-methyltransferase.
 
   
 0.807
cysG2
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.776
nirH
Heme biosynthesis protein NirH.
     
 0.692
ccmC
Heme exporter protein C.
  
  
 0.615
Your Current Organism:
Haloarcula marismortui
NCBI taxonomy Id: 272569
Other names: H. marismortui ATCC 43049, Haloarcula marismortui ATCC 43049, Haloarcula marismortui str. ATCC 43049, Haloarcula marismortui strain ATCC 43049
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