STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aupAcetoin utilization protein. (335 aa)    
Predicted Functional Partners:
hpyA
Archaeal histone A1.
   
 
 0.914
sir2
Transcriptional regulator Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily.
   
 
 0.837
rpl40E
50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family.
    
  0.814
rpa
Replication A related protein.
  
   0.811
smc2
Chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.752
tbpE
TATA-box binding protein E; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
  
 0.747
cdc48b
Cell division control protein 48.
 
 
 0.709
cdc48c
Cell division control protein 48.
 
 
 0.709
ruvB
Holliday junction DNA helicase.
 
 
 0.708
cdc48d
Cell division control protein 48.
 
 
 0.706
Your Current Organism:
Haloarcula marismortui
NCBI taxonomy Id: 272569
Other names: H. marismortui ATCC 43049, Haloarcula marismortui ATCC 43049, Haloarcula marismortui str. ATCC 43049, Haloarcula marismortui strain ATCC 43049
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.