STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpxOPutative flavoprotein monooxygenase; Catalyzes the hydroxylation of urate to 5-hydroxyisourate (HIU); Belongs to the FAD-dependent urate hydroxylase family. (384 aa)    
Predicted Functional Partners:
acs
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 
 0.789
KPN_01666
Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
 
  0.782
KPN_01665
Hypothetical protein.
 
     0.733
nirD
Nitrite reductase small subunit.
     
 0.695
KPN_01870
NADH oxidoreductase for HCP.
     
 0.690
KPN_01872
3-phenylpropionate dioxygenase, alpha subunit.
   
 
 0.680
KPN_00488
Hypothetical protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
  
 
  0.673
KPN_01616
High-affinity branched-chain amino acid transport protein (ABC superfamily, peri_bind).
   
  
 0.665
KPN_03371
Putative ferredoxin.
     
 0.661
KPN_01661
Putative oxidoreductase.
  
  
 0.618
Your Current Organism:
Klebsiella pneumoniae MGH78578
NCBI taxonomy Id: 272620
Other names: K. pneumoniae subsp. pneumoniae MGH 78578, Klebsiella pneumoniae MCG 78578, Klebsiella pneumoniae str. MCG 78578, Klebsiella pneumoniae subsp. pneumoniae ATCC 700721, Klebsiella pneumoniae subsp. pneumoniae MGH 78578, Klebsiella pneumoniae subsp. pneumoniae str. MGH 78578, Klebsiella pneumoniae subsp. pneumoniae strain MGH 78578
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