node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KPN_04708 | arcB | KPN_04708 | KPN_03619 | Putative ATP-dependent helicase. | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | 0.540 |
KPN_04708 | barA | KPN_04708 | KPN_03128 | Putative ATP-dependent helicase. | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | 0.550 |
KPN_04708 | prsA | KPN_04708 | KPN_02238 | Putative ATP-dependent helicase. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.508 |
KPN_04708 | rnr | KPN_04708 | KPN_04578 | Putative ATP-dependent helicase. | RNase R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. | 0.590 |
KPN_04708 | yffH | KPN_04708 | KPN_02801 | Putative ATP-dependent helicase. | Conserved protein, MutT-like protein; Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP- mannose as its preferred substrate, yielding GMP and mannose-1- phosphate. | 0.586 |
KPN_04708 | yjeF | KPN_04708 | KPN_04565 | Putative ATP-dependent helicase. | Putative kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers [...] | 0.877 |
aegA | yffH | KPN_02802 | KPN_02801 | Putative oxidoreductase, Fe-S subunit (anaerobically expressed gene). | Conserved protein, MutT-like protein; Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP- mannose as its preferred substrate, yielding GMP and mannose-1- phosphate. | 0.632 |
aegA | ypfG | KPN_02802 | KPN_02800 | Putative oxidoreductase, Fe-S subunit (anaerobically expressed gene). | Hypothetical protein. | 0.429 |
arcB | KPN_04708 | KPN_03619 | KPN_04708 | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | Putative ATP-dependent helicase. | 0.540 |
arcB | barA | KPN_03619 | KPN_03128 | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | 0.999 |
arcB | metH-2 | KPN_03619 | KPN_04399 | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.535 |
arcB | prsA | KPN_03619 | KPN_02238 | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.648 |
arcB | yffH | KPN_03619 | KPN_02801 | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | Conserved protein, MutT-like protein; Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP- mannose as its preferred substrate, yielding GMP and mannose-1- phosphate. | 0.725 |
barA | KPN_04708 | KPN_03128 | KPN_04708 | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | Putative ATP-dependent helicase. | 0.550 |
barA | arcB | KPN_03128 | KPN_03619 | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | 0.999 |
barA | metH-2 | KPN_03128 | KPN_04399 | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.462 |
barA | prsA | KPN_03128 | KPN_02238 | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.775 |
barA | yffH | KPN_03128 | KPN_02801 | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | Conserved protein, MutT-like protein; Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP- mannose as its preferred substrate, yielding GMP and mannose-1- phosphate. | 0.707 |
birA | yffH | KPN_04351 | KPN_02801 | Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Conserved protein, MutT-like protein; Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP- mannose as its preferred substrate, yielding GMP and mannose-1- phosphate. | 0.605 |
birA | yjeF | KPN_04351 | KPN_04565 | Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Putative kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers [...] | 0.459 |