STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpF-2MIP channel, glycerol diffusion; Belongs to the MIP/aquaporin (TC 1.A.8) family. (283 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
 
 
 0.956
glpD
Sn-glycerol-3-phosphate dehydrogenase (aerobic); Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.824
glpA
Sn-glycerol-3-phosphate dehydrogenase (anaerobic), large subunit; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.808
KPN_00591
Putative carbohydrate kinase; Belongs to the FGGY kinase family.
 
 
 0.756
glpQ
Glycerophosphodiester phosphodiesterase, periplasmic.
  
 
 0.742
glpT
Sn-glycerol-3-phosphate permease.
 
  
 0.699
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.673
pgtP
Phosphoglycerate transport: transporter.
 
  
 0.647
dhaM
Putative PTS hybrid protein; Belongs to the PEP-utilizing enzyme family.
  
  
 0.637
wecF
TDP-Fuc4NAc:lipidIIFuc4NAc transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family.
  
 
 0.615
Your Current Organism:
Klebsiella pneumoniae MGH78578
NCBI taxonomy Id: 272620
Other names: K. pneumoniae subsp. pneumoniae MGH 78578, Klebsiella pneumoniae MCG 78578, Klebsiella pneumoniae str. MCG 78578, Klebsiella pneumoniae subsp. pneumoniae ATCC 700721, Klebsiella pneumoniae subsp. pneumoniae MGH 78578, Klebsiella pneumoniae subsp. pneumoniae str. MGH 78578, Klebsiella pneumoniae subsp. pneumoniae strain MGH 78578
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