STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyaAAdenylate cyclase; Belongs to the adenylyl cyclase class-1 family. (850 aa)    
Predicted Functional Partners:
crp
Cyclic AMP receptor protein.
  
  
 0.939
cpdA
Cyclic 3',5'-adenosine monophosphate phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
  
 0.934
cpdA-2
Putative phosphohydrolase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
     
 0.837
crr
Glucose-specific PTS system enzyme IIA component.
     
 0.809
nagE
PTS family enzyme IIC/enzyme IIB/enzyme IIC; N-acetylglucosamine-specific.
     
 0.806
KPN_02578
Putative cellobiose-specific PTS permease.
     
 0.806
hemY
Hypothetical protein; A late step of protoheme IX synthesis.
 
     0.773
hemX
Uroporphyrinogen III methylase.
 
     0.768
yciS
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
   
 0.766
KPN_00514
Sucrose-specific enzyme II.
     
 0.755
Your Current Organism:
Klebsiella pneumoniae MGH78578
NCBI taxonomy Id: 272620
Other names: K. pneumoniae subsp. pneumoniae MGH 78578, Klebsiella pneumoniae MCG 78578, Klebsiella pneumoniae str. MCG 78578, Klebsiella pneumoniae subsp. pneumoniae ATCC 700721, Klebsiella pneumoniae subsp. pneumoniae MGH 78578, Klebsiella pneumoniae subsp. pneumoniae str. MGH 78578, Klebsiella pneumoniae subsp. pneumoniae strain MGH 78578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.