STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iolEPutative sugar phosphate isomerases/epimerases; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). Belongs to the IolE/MocC family. (299 aa)    
Predicted Functional Partners:
KPN_04674
Putative acetolactate synthase large subunit; Belongs to the TPP enzyme family.
 
 
 0.992
iolG
Putative NADH-dependent dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).
 
 
 0.988
KPN_04669
Hypothetical protein.
 
 
  0.958
KPN_04676
Putative epimerase/isomerase.
 
  
 0.950
KPN_00507
Putative oxidoreductase.
 
 
 0.943
KPN_04671
Hypothetical protein.
 
  
 0.910
KPN_04673
Putative carbohydrate kinase.
 
 0.896
KPN_00505
Putative oxidoreductase.
 
 0.864
KPN_01796
Putative epimerase/isomerase.
  
  
 
0.750
tyrA
Bifunctional chorismate mutase T/prephenate dehydrogenase.
     
 0.710
Your Current Organism:
Klebsiella pneumoniae MGH78578
NCBI taxonomy Id: 272620
Other names: K. pneumoniae subsp. pneumoniae MGH 78578, Klebsiella pneumoniae MCG 78578, Klebsiella pneumoniae str. MCG 78578, Klebsiella pneumoniae subsp. pneumoniae ATCC 700721, Klebsiella pneumoniae subsp. pneumoniae MGH 78578, Klebsiella pneumoniae subsp. pneumoniae str. MGH 78578, Klebsiella pneumoniae subsp. pneumoniae strain MGH 78578
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