node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LBA1745 | NrdF | LBA1745 | LBA1750 | COG0194 Guanylate kinase. | Ribonucleotide reductase. | 0.907 |
LBA1745 | aprT | LBA1745 | LBA1242 | COG0194 Guanylate kinase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.954 |
LBA1745 | gmk | LBA1745 | LBA1325 | COG0194 Guanylate kinase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.936 |
LBA1745 | guaA | LBA1745 | LBA0245 | COG0194 Guanylate kinase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.953 |
LBA1745 | guaC | LBA1745 | LBA1893 | COG0194 Guanylate kinase. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.914 |
LBA1745 | hprT | LBA1745 | LBA0613 | COG0194 Guanylate kinase. | Hypothetical protein; COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.917 |
LBA1745 | kpyK | LBA1745 | LBA0957 | COG0194 Guanylate kinase. | Pyruvate kinase; COG3848 Phosphohistidine swiveling domain; Belongs to the pyruvate kinase family. | 0.940 |
LBA1745 | relA | LBA1745 | LBA0932 | COG0194 Guanylate kinase. | ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.925 |
LBA1745 | rpoZ | LBA1745 | LBA1324 | COG0194 Guanylate kinase. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.705 |
LBA1745 | xpt | LBA1745 | LBA0240 | COG0194 Guanylate kinase. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.953 |
NrdF | LBA1745 | LBA1750 | LBA1745 | Ribonucleotide reductase. | COG0194 Guanylate kinase. | 0.907 |
NrdF | gmk | LBA1750 | LBA1325 | Ribonucleotide reductase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.907 |
NrdF | kpyK | LBA1750 | LBA0957 | Ribonucleotide reductase. | Pyruvate kinase; COG3848 Phosphohistidine swiveling domain; Belongs to the pyruvate kinase family. | 0.936 |
NrdF | relA | LBA1750 | LBA0932 | Ribonucleotide reductase. | ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.901 |
aprT | LBA1745 | LBA1242 | LBA1745 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | COG0194 Guanylate kinase. | 0.954 |
aprT | gmk | LBA1242 | LBA1325 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.951 |
aprT | guaA | LBA1242 | LBA0245 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.990 |
aprT | guaC | LBA1242 | LBA1893 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.946 |
aprT | hprT | LBA1242 | LBA0613 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypothetical protein; COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.967 |
aprT | xpt | LBA1242 | LBA0240 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.929 |