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truA protein (Lactococcus lactis Il1403) - STRING interaction network
"truA" - tRNA pseudouridine synthase A in Lactococcus lactis Il1403
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (253 aa)    
Predicted Functional Partners:
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (329 aa)
   
 
  0.943
ydiB
Probable tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (406 aa)
     
   
  0.862
ychF
Energy-coupling factor transporter transmembrane protein EcfT; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (266 aa)
 
        0.850
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3’- to 5’- polarity. Unwinds branched duplex DNA (Y-DNA) (666 aa)
 
   
  0.828
thiD2
Phosphomethylpyrimidine kinase; EVIDENCE BY HOMOLOGY BIO02.11 Thiamine. functions also in a salvage pathway (262 aa)
   
        0.822
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1’ of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1’ of the ribose to form th [...] (382 aa)
   
   
  0.816
gidA
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family (625 aa)
   
   
  0.813
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (217 aa)
   
 
  0.808
leuS
Leucine--tRNA ligase; EVIDENCE BY HOMOLOGY BIO12.01 Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family (829 aa)
   
   
  0.794
lepA
Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (607 aa)
 
 
  0.791
Your Current Organism:
Lactococcus lactis Il1403
NCBI taxonomy Id: 272623
Other names: L. lactis subsp. lactis Il1403, Lactococcus lactis Il1403, Lactococcus lactis subsp. lactis Il1403, Lactococcus lactis subsp. lactis str. Il1403, Lactococcus lactis subsp. lactis strain Il1403
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