node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
guaB | lpg0095 | lpg1723 | lpg0095 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Cytosolic IMP-GMP specific 5'-nucleotidase. | 0.684 |
guaB | lpg1912 | lpg1723 | lpg1912 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Sensory box histidine kinase/response regulator. | 0.616 |
guaB | lpg2180 | lpg1723 | lpg2180 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Sensory box histidine kinase/response regulator. | 0.631 |
guaB | pleD | lpg1723 | lpg0230 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Sensor histidine kinase. | 0.666 |
guaB | pyrF | lpg1723 | lpg1425 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Orotidine 5'-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.546 |
legG1 | legS1 | lpg1976 | lpg2588 | UVB-resistance protein UVR8; Conserved gene; RCC-1. | Acid sphingomyelinase-like phosphodiesterase. | 0.573 |
legG1 | lpg0095 | lpg1976 | lpg0095 | UVB-resistance protein UVR8; Conserved gene; RCC-1. | Cytosolic IMP-GMP specific 5'-nucleotidase. | 0.687 |
legS1 | legG1 | lpg2588 | lpg1976 | Acid sphingomyelinase-like phosphodiesterase. | UVB-resistance protein UVR8; Conserved gene; RCC-1. | 0.573 |
legS1 | lpg0095 | lpg2588 | lpg0095 | Acid sphingomyelinase-like phosphodiesterase. | Cytosolic IMP-GMP specific 5'-nucleotidase. | 0.697 |
legS1 | pleD | lpg2588 | lpg0230 | Acid sphingomyelinase-like phosphodiesterase. | Sensor histidine kinase. | 0.451 |
lpg0095 | guaB | lpg0095 | lpg1723 | Cytosolic IMP-GMP specific 5'-nucleotidase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.684 |
lpg0095 | legG1 | lpg0095 | lpg1976 | Cytosolic IMP-GMP specific 5'-nucleotidase. | UVB-resistance protein UVR8; Conserved gene; RCC-1. | 0.687 |
lpg0095 | legS1 | lpg0095 | lpg2588 | Cytosolic IMP-GMP specific 5'-nucleotidase. | Acid sphingomyelinase-like phosphodiesterase. | 0.697 |
lpg0095 | lpg1445 | lpg0095 | lpg1445 | Cytosolic IMP-GMP specific 5'-nucleotidase. | Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.792 |
lpg0095 | lpg1912 | lpg0095 | lpg1912 | Cytosolic IMP-GMP specific 5'-nucleotidase. | Sensory box histidine kinase/response regulator. | 0.691 |
lpg0095 | lpg2180 | lpg0095 | lpg2180 | Cytosolic IMP-GMP specific 5'-nucleotidase. | Sensory box histidine kinase/response regulator. | 0.697 |
lpg0095 | pleD | lpg0095 | lpg0230 | Cytosolic IMP-GMP specific 5'-nucleotidase. | Sensor histidine kinase. | 0.645 |
lpg0095 | pyrF | lpg0095 | lpg1425 | Cytosolic IMP-GMP specific 5'-nucleotidase. | Orotidine 5'-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.648 |
lpg0095 | sucD | lpg0095 | lpg0535 | Cytosolic IMP-GMP specific 5'-nucleotidase. | Succinyl CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.642 |
lpg0095 | vacB | lpg0095 | lpg0092 | Cytosolic IMP-GMP specific 5'-nucleotidase. | (exo)ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.664 |