node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cbpA | cl | lpg2263 | lpg0818 | Curved DNA binding protein DnaJ. | ATP binding protease component ClpA; Belongs to the ClpA/ClpB family. | 0.794 |
cbpA | clpB | lpg2263 | lpg1750 | Curved DNA binding protein DnaJ. | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.794 |
cbpA | dnaK | lpg2263 | lpg2025 | Curved DNA binding protein DnaJ. | Chaperone protein DnaK, heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
cbpA | grpE | lpg2263 | lpg2026 | Curved DNA binding protein DnaJ. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.971 |
cbpA | htpA | lpg2263 | lpg0687 | Curved DNA binding protein DnaJ. | Hsp10, 10 kDa chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.782 |
cbpA | htpB | lpg2263 | lpg0688 | Curved DNA binding protein DnaJ. | Hsp60, 60K heat shock protein HtpB; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | 0.915 |
cbpA | htpG | lpg2263 | lpg1369 | Curved DNA binding protein DnaJ. | Chaperone Hsp90 HtpG; Molecular chaperone. Has ATPase activity. | 0.985 |
cbpA | rplP | lpg2263 | lpg0336 | Curved DNA binding protein DnaJ. | 50S ribosomal protein L16/(L10E); Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.726 |
cl | cbpA | lpg0818 | lpg2263 | ATP binding protease component ClpA; Belongs to the ClpA/ClpB family. | Curved DNA binding protein DnaJ. | 0.794 |
cl | dnaJ | lpg0818 | lpg2024 | ATP binding protease component ClpA; Belongs to the ClpA/ClpB family. | Heat shock protein DnaJ, chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interact [...] | 0.789 |
cl | dnaK | lpg0818 | lpg2025 | ATP binding protease component ClpA; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK, heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.989 |
cl | grpE | lpg0818 | lpg2026 | ATP binding protease component ClpA; Belongs to the ClpA/ClpB family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.870 |
cl | htpA | lpg0818 | lpg0687 | ATP binding protease component ClpA; Belongs to the ClpA/ClpB family. | Hsp10, 10 kDa chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.738 |
cl | htpB | lpg0818 | lpg0688 | ATP binding protease component ClpA; Belongs to the ClpA/ClpB family. | Hsp60, 60K heat shock protein HtpB; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | 0.697 |
cl | htpG | lpg0818 | lpg1369 | ATP binding protease component ClpA; Belongs to the ClpA/ClpB family. | Chaperone Hsp90 HtpG; Molecular chaperone. Has ATPase activity. | 0.796 |
cl | lpg1042 | lpg0818 | lpg1042 | ATP binding protease component ClpA; Belongs to the ClpA/ClpB family. | Hypothetical protein. | 0.745 |
clpB | cbpA | lpg1750 | lpg2263 | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Curved DNA binding protein DnaJ. | 0.794 |
clpB | dnaJ | lpg1750 | lpg2024 | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Heat shock protein DnaJ, chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interact [...] | 0.789 |
clpB | dnaK | lpg1750 | lpg2025 | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK, heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.989 |
clpB | grpE | lpg1750 | lpg2026 | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.870 |