node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fum | gltA | lpg2937 | lpg1415 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Citrate synthase; Belongs to the citrate synthase family. | 0.780 |
fum | icd | lpg2937 | lpg0816 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Isocitrate dehydrogenase, NADP-dependent. | 0.798 |
fum | lpg0947 | lpg2937 | lpg0947 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 2-oxoglutarate ferredoxin oxidoreductase alpha subunit. | 0.821 |
fum | lpg1530 | lpg2937 | lpg1530 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.648 |
fum | mdh | lpg2937 | lpg2352 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.947 |
fum | sdhA-2 | lpg2937 | lpg0530 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Succinate dehydrogenase flavoprotein subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.996 |
fum | sucC | lpg2937 | lpg0534 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.834 |
fum | sucD | lpg2937 | lpg0535 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Succinyl CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.915 |
gap | icd | lpg0138 | lpg0816 | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Isocitrate dehydrogenase, NADP-dependent. | 0.458 |
gap | lpg0947 | lpg0138 | lpg0947 | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 2-oxoglutarate ferredoxin oxidoreductase alpha subunit. | 0.406 |
gap | mdh | lpg0138 | lpg2352 | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.906 |
gltA | fum | lpg1415 | lpg2937 | Citrate synthase; Belongs to the citrate synthase family. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.780 |
gltA | icd | lpg1415 | lpg0816 | Citrate synthase; Belongs to the citrate synthase family. | Isocitrate dehydrogenase, NADP-dependent. | 0.870 |
gltA | lpg0947 | lpg1415 | lpg0947 | Citrate synthase; Belongs to the citrate synthase family. | 2-oxoglutarate ferredoxin oxidoreductase alpha subunit. | 0.782 |
gltA | lpg1923 | lpg1415 | lpg1923 | Citrate synthase; Belongs to the citrate synthase family. | Ferredoxin II (4Fe-4S); Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | 0.422 |
gltA | mdh | lpg1415 | lpg2352 | Citrate synthase; Belongs to the citrate synthase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.974 |
gltA | sdhA-2 | lpg1415 | lpg0530 | Citrate synthase; Belongs to the citrate synthase family. | Succinate dehydrogenase flavoprotein subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.904 |
gltA | sucC | lpg1415 | lpg0534 | Citrate synthase; Belongs to the citrate synthase family. | Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.981 |
gltA | sucD | lpg1415 | lpg0535 | Citrate synthase; Belongs to the citrate synthase family. | Succinyl CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.807 |
icd | fum | lpg0816 | lpg2937 | Isocitrate dehydrogenase, NADP-dependent. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.798 |