node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
pdp | pyrR | gene:17566459 | gene:17566312 | Pdp protein; Similar to pyrimidine-nucleoside phosphorylase. | Pyrimidine operon regulatory protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.915 |
pdp | udk | gene:17566459 | gene:17565863 | Pdp protein; Similar to pyrimidine-nucleoside phosphorylase. | Similar to Uridine kinase. | 0.928 |
pdp | upp | gene:17566459 | gene:17567062 | Pdp protein; Similar to pyrimidine-nucleoside phosphorylase. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.966 |
pyrAB | pyrB | gene:17566307 | gene:17566310 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Highly similar to aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
pyrAB | pyrC | gene:17566307 | gene:17566309 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
pyrAB | pyrE | gene:17566307 | gene:17566303 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.995 |
pyrAB | pyrF | gene:17566307 | gene:17566304 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.996 |
pyrAB | pyrP | gene:17566307 | gene:17566311 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | PyrP protein; Highly similar to uracil permease. | 0.940 |
pyrAB | pyrR | gene:17566307 | gene:17566312 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Pyrimidine operon regulatory protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.935 |
pyrAB | smbA | gene:17566307 | gene:17565681 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.453 |
pyrAB | upp | gene:17566307 | gene:17567062 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.540 |
pyrB | pyrAB | gene:17566310 | gene:17566307 | Highly similar to aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | 0.999 |
pyrB | pyrC | gene:17566310 | gene:17566309 | Highly similar to aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
pyrB | pyrE | gene:17566310 | gene:17566303 | Highly similar to aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.997 |
pyrB | pyrF | gene:17566310 | gene:17566304 | Highly similar to aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.997 |
pyrB | pyrP | gene:17566310 | gene:17566311 | Highly similar to aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | PyrP protein; Highly similar to uracil permease. | 0.996 |
pyrB | pyrR | gene:17566310 | gene:17566312 | Highly similar to aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Pyrimidine operon regulatory protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.998 |
pyrB | smbA | gene:17566310 | gene:17565681 | Highly similar to aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.433 |
pyrB | upp | gene:17566310 | gene:17567062 | Highly similar to aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.662 |
pyrC | pyrAB | gene:17566309 | gene:17566307 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | 0.999 |