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rutC protein (Methylobacterium extorquens AM1) - STRING interaction network
"rutC" - Putative aminoacrylate peracid reductase RutC in Methylobacterium extorquens AM1
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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rutCPutative aminoacrylate peracid reductase RutC; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (130 aa)    
Predicted Functional Partners:
rutB
Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB; In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2; Belongs to the isochorismatase family. RutB subfamily (248 aa)
 
 
  0.997
rutD
Putative aminoacrylate hydrolase RutD; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (260 aa)
 
   
    0.996
rutA
Pyrimidine monooxygenase RutA; Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (364 aa)
 
        0.970
ACS39509.1
FMN reductase (NADH) RutF; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (201 aa)
 
   
  0.870
ACS39514.1
Putative transcriptional regulator, TetR/AcrR family; Evidence 3 - Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr - putative regulator (213 aa)
 
          0.669
ACS40975.1
FMN reductase (NADH) RutF; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (172 aa)
 
   
  0.448
ACS39508.1
ABC family transporter substrate-binding protein; Evidence 2b - Function of strongly homologous gene; Product type t - transporter (284 aa)
              0.420
ACS39507.1
ABC family transporter permease protein; Evidence 2b - Function of strongly homologous gene; Product type t - transporter (301 aa)
              0.420
ACS39506.1
ATP-binding protein of ABC family transporter; Evidence 2b - Function of strongly homologous gene; Product type t - transporter (321 aa)
              0.420
Your Current Organism:
Methylobacterium extorquens AM1
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylobacterium extorquens str. AM1, Methylobacterium extorquens strain AM1, Pseudomonas AM1, Pseudomonas sp. AM1
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