node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ML0376 | ML0377 | gene:17574195 | gene:17574196 | Putative membrane protein; Unknown function. Contains hydrophobic, possible membrane-spanning region near the N-terminus. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | 0.859 |
ML0376 | ML0378 | gene:17574195 | gene:17574197 | Putative membrane protein; Unknown function. Contains hydrophobic, possible membrane-spanning region near the N-terminus. | Similar to M. tuberculosis rimI, Rv3420c, putative ribosomal protein S18 acetyltransferase, TR:Q50708 (EMBL:Z77165) (158 aa); Fasta score E(): 0, 72.1% identity in 154 aa overlap in the C-terminus and to M. tuberculosis Rv3421c hypothetical protein, SW:YY21_MYCTU (Q50707) (211 aa); Fasta score E(): 0, 75.6% identity in 205 aa overlap in the N-terminus. Appears to be a fusion of two M. tuberculosis homologues. Similar to many hypothetical acetyltransferases. Previously sequenced as SW:YY21_MYCLE (Q49857) (359 aa); Fasta score E(): 0, 100.0% identity in 359 aa overlap. Contains Pfam matc [...] | 0.790 |
ML0376 | alr | gene:17574195 | gene:17574194 | Putative membrane protein; Unknown function. Contains hydrophobic, possible membrane-spanning region near the N-terminus. | Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.860 |
ML0376 | gcp | gene:17574195 | gene:17574198 | Putative membrane protein; Unknown function. Contains hydrophobic, possible membrane-spanning region near the N-terminus. | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.859 |
ML0377 | ML0376 | gene:17574196 | gene:17574195 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | Putative membrane protein; Unknown function. Contains hydrophobic, possible membrane-spanning region near the N-terminus. | 0.859 |
ML0377 | ML0378 | gene:17574196 | gene:17574197 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | Similar to M. tuberculosis rimI, Rv3420c, putative ribosomal protein S18 acetyltransferase, TR:Q50708 (EMBL:Z77165) (158 aa); Fasta score E(): 0, 72.1% identity in 154 aa overlap in the C-terminus and to M. tuberculosis Rv3421c hypothetical protein, SW:YY21_MYCTU (Q50707) (211 aa); Fasta score E(): 0, 75.6% identity in 205 aa overlap in the N-terminus. Appears to be a fusion of two M. tuberculosis homologues. Similar to many hypothetical acetyltransferases. Previously sequenced as SW:YY21_MYCLE (Q49857) (359 aa); Fasta score E(): 0, 100.0% identity in 359 aa overlap. Contains Pfam matc [...] | 0.989 |
ML0377 | alr | gene:17574196 | gene:17574194 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.983 |
ML0377 | gcp | gene:17574196 | gene:17574198 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.986 |
ML0378 | ML0376 | gene:17574197 | gene:17574195 | Similar to M. tuberculosis rimI, Rv3420c, putative ribosomal protein S18 acetyltransferase, TR:Q50708 (EMBL:Z77165) (158 aa); Fasta score E(): 0, 72.1% identity in 154 aa overlap in the C-terminus and to M. tuberculosis Rv3421c hypothetical protein, SW:YY21_MYCTU (Q50707) (211 aa); Fasta score E(): 0, 75.6% identity in 205 aa overlap in the N-terminus. Appears to be a fusion of two M. tuberculosis homologues. Similar to many hypothetical acetyltransferases. Previously sequenced as SW:YY21_MYCLE (Q49857) (359 aa); Fasta score E(): 0, 100.0% identity in 359 aa overlap. Contains Pfam matc [...] | Putative membrane protein; Unknown function. Contains hydrophobic, possible membrane-spanning region near the N-terminus. | 0.790 |
ML0378 | ML0377 | gene:17574197 | gene:17574196 | Similar to M. tuberculosis rimI, Rv3420c, putative ribosomal protein S18 acetyltransferase, TR:Q50708 (EMBL:Z77165) (158 aa); Fasta score E(): 0, 72.1% identity in 154 aa overlap in the C-terminus and to M. tuberculosis Rv3421c hypothetical protein, SW:YY21_MYCTU (Q50707) (211 aa); Fasta score E(): 0, 75.6% identity in 205 aa overlap in the N-terminus. Appears to be a fusion of two M. tuberculosis homologues. Similar to many hypothetical acetyltransferases. Previously sequenced as SW:YY21_MYCLE (Q49857) (359 aa); Fasta score E(): 0, 100.0% identity in 359 aa overlap. Contains Pfam matc [...] | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | 0.989 |
ML0378 | alr | gene:17574197 | gene:17574194 | Similar to M. tuberculosis rimI, Rv3420c, putative ribosomal protein S18 acetyltransferase, TR:Q50708 (EMBL:Z77165) (158 aa); Fasta score E(): 0, 72.1% identity in 154 aa overlap in the C-terminus and to M. tuberculosis Rv3421c hypothetical protein, SW:YY21_MYCTU (Q50707) (211 aa); Fasta score E(): 0, 75.6% identity in 205 aa overlap in the N-terminus. Appears to be a fusion of two M. tuberculosis homologues. Similar to many hypothetical acetyltransferases. Previously sequenced as SW:YY21_MYCLE (Q49857) (359 aa); Fasta score E(): 0, 100.0% identity in 359 aa overlap. Contains Pfam matc [...] | Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.856 |
ML0378 | gcp | gene:17574197 | gene:17574198 | Similar to M. tuberculosis rimI, Rv3420c, putative ribosomal protein S18 acetyltransferase, TR:Q50708 (EMBL:Z77165) (158 aa); Fasta score E(): 0, 72.1% identity in 154 aa overlap in the C-terminus and to M. tuberculosis Rv3421c hypothetical protein, SW:YY21_MYCTU (Q50707) (211 aa); Fasta score E(): 0, 75.6% identity in 205 aa overlap in the N-terminus. Appears to be a fusion of two M. tuberculosis homologues. Similar to many hypothetical acetyltransferases. Previously sequenced as SW:YY21_MYCLE (Q49857) (359 aa); Fasta score E(): 0, 100.0% identity in 359 aa overlap. Contains Pfam matc [...] | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.999 |
ML2502 | ald | gene:17576366 | gene:17575373 | Similar to Mycobacterium tuberculosis probable aspartate aminotransferase RV0337C SW:AAT_MYCTU (O33267) fasta scores: E(): 0, 91.4% id in 429 aa and to Bacillus stearothermophilus aspartate aminotransferase AspC SW:AAT_BACST (Q59228) fasta scores: E(): 0, 32.4% id in 389 aa. Contains Pfam match to entry PF00155 aminotran_1, Aminotransferases class-I. | Highly similar to many alanine dehydrogenases (EC 1.4.1.1) including: Bacillus sphaericus SW:DHA_BACSH (P175566) (372 aa); Fasta score E(): 0, 53.4% identity in 365 aa overlap and Mycobacterium tuberculosis RV2780 SW:DHA_MYCTU (P30234) (371 aa); Fasta score E(): 0, 85.4% identity in 371 aa overlap. Contains Pfam match to entry PF01262 AlaDh_PNT, Alanine dehydrogenase/pyridine nucleotide transhydrogenase. Contains PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. Contains PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1; Be [...] | 0.904 |
ML2502 | alr | gene:17576366 | gene:17574194 | Similar to Mycobacterium tuberculosis probable aspartate aminotransferase RV0337C SW:AAT_MYCTU (O33267) fasta scores: E(): 0, 91.4% id in 429 aa and to Bacillus stearothermophilus aspartate aminotransferase AspC SW:AAT_BACST (Q59228) fasta scores: E(): 0, 32.4% id in 389 aa. Contains Pfam match to entry PF00155 aminotran_1, Aminotransferases class-I. | Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.814 |
ald | ML2502 | gene:17575373 | gene:17576366 | Highly similar to many alanine dehydrogenases (EC 1.4.1.1) including: Bacillus sphaericus SW:DHA_BACSH (P175566) (372 aa); Fasta score E(): 0, 53.4% identity in 365 aa overlap and Mycobacterium tuberculosis RV2780 SW:DHA_MYCTU (P30234) (371 aa); Fasta score E(): 0, 85.4% identity in 371 aa overlap. Contains Pfam match to entry PF01262 AlaDh_PNT, Alanine dehydrogenase/pyridine nucleotide transhydrogenase. Contains PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. Contains PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1; Be [...] | Similar to Mycobacterium tuberculosis probable aspartate aminotransferase RV0337C SW:AAT_MYCTU (O33267) fasta scores: E(): 0, 91.4% id in 429 aa and to Bacillus stearothermophilus aspartate aminotransferase AspC SW:AAT_BACST (Q59228) fasta scores: E(): 0, 32.4% id in 389 aa. Contains Pfam match to entry PF00155 aminotran_1, Aminotransferases class-I. | 0.904 |
ald | alr | gene:17575373 | gene:17574194 | Highly similar to many alanine dehydrogenases (EC 1.4.1.1) including: Bacillus sphaericus SW:DHA_BACSH (P175566) (372 aa); Fasta score E(): 0, 53.4% identity in 365 aa overlap and Mycobacterium tuberculosis RV2780 SW:DHA_MYCTU (P30234) (371 aa); Fasta score E(): 0, 85.4% identity in 371 aa overlap. Contains Pfam match to entry PF01262 AlaDh_PNT, Alanine dehydrogenase/pyridine nucleotide transhydrogenase. Contains PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. Contains PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1; Be [...] | Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.947 |
alr | ML0376 | gene:17574194 | gene:17574195 | Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Putative membrane protein; Unknown function. Contains hydrophobic, possible membrane-spanning region near the N-terminus. | 0.860 |
alr | ML0377 | gene:17574194 | gene:17574196 | Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | 0.983 |
alr | ML0378 | gene:17574194 | gene:17574197 | Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Similar to M. tuberculosis rimI, Rv3420c, putative ribosomal protein S18 acetyltransferase, TR:Q50708 (EMBL:Z77165) (158 aa); Fasta score E(): 0, 72.1% identity in 154 aa overlap in the C-terminus and to M. tuberculosis Rv3421c hypothetical protein, SW:YY21_MYCTU (Q50707) (211 aa); Fasta score E(): 0, 75.6% identity in 205 aa overlap in the N-terminus. Appears to be a fusion of two M. tuberculosis homologues. Similar to many hypothetical acetyltransferases. Previously sequenced as SW:YY21_MYCLE (Q49857) (359 aa); Fasta score E(): 0, 100.0% identity in 359 aa overlap. Contains Pfam matc [...] | 0.856 |
alr | ML2502 | gene:17574194 | gene:17576366 | Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Similar to Mycobacterium tuberculosis probable aspartate aminotransferase RV0337C SW:AAT_MYCTU (O33267) fasta scores: E(): 0, 91.4% id in 429 aa and to Bacillus stearothermophilus aspartate aminotransferase AspC SW:AAT_BACST (Q59228) fasta scores: E(): 0, 32.4% id in 389 aa. Contains Pfam match to entry PF00155 aminotran_1, Aminotransferases class-I. | 0.814 |