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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ML0393Putative hydrolase; Similar to M. tuberculosis Rv3400, hypothetical protein, SW:YY00_MYCTU (Q50725) (262 aa); Fasta score E(): 0, 74.4% identity in 262 aa overlap. Previously sequenced as SW:YY00_MYCLE (Q49741) (261 aa); Fasta score E(): 0, 100.0% identity in 261 aa overlap. Contains Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase. (261 aa)    
Predicted Functional Partners:
ML0392
Putative sugar phosphorylase; Similar to M. tuberculosis Rv3401, conserved hypothetical protein, SW:YY01_MYCTU (Q50724) (786 aa); Fasta score E(): 0, 91.4% identity in 782 aa overlap. Shows weak similarity to Lactobacillus sanfranciscensis mapA, maltose phosphorylase, TR:O87772 (EMBL:AJ224340) (753 aa); Fasta score E(): 1.4e-13, 29.0% identity in 769 aa overlap. Similar to many bacterial hypothetical proteins e.g. Streptomyces coelicolor SCF42.31C, putative glycosyl transferase, TR:CAB69693 (EMBL:AL137165) (792 aa); Fasta score E(): 0, 58.9% identity in 790 aa overlap. Previously seque [...]
  
 0.996
otsB2
Putative trehalose-6-phosphate phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
   
 0.530
guaA
Putative GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
    0.518
ML0051
Similar to PPE-family proteins from M. tuberculosis e.g. Rv3873, PPE-family protein, TR:O69738 (EMBL:AL123456) (368 aa); Fasta score E(): 6.1e-32, 46.2% identity in 288 aa overlap. Lacks the PPE motif at the N-terminus. Previously sequenced as TR:O33085 (EMBL:Y14967) (302 aa); Fasta score E(): 0, 100.0% identity in 302 aa overlap. Contains Pfam match to entry PF00823 PPE, PPE family; N-terminus is similar to the N-termini of ML0539, ML1828 and ML1991.
      
 0.487
Your Current Organism:
Mycobacterium leprae
NCBI taxonomy Id: 272631
Other names: M. leprae TN, Mycobacterium leprae TN, Mycobacterium leprae str. TN, Mycobacterium leprae strain TN
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