Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ML0450 | ML0451 | gene:17574271 | gene:17574272 | Putative pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Similar to M. tuberculosis Rv2609c, conserved hypothetical protein, TR:O06205 (EMBL:AL123456) (351 aa); Fasta score E(): 0, 77.7% identity in 336 aa overlap. Similar, in part, to hypothetical proteins from Streptomyces coelicolor e.g. SC2E1.17, hypothetical protein, TR:O69888 (EMBL:AL023797) (172 aa); Fasta score E(): 2e-13, 43.3% identity in 150 aa overlap. Previously sequenced as TR:O07146 (EMBL:Z96801) (349 aa); Fasta score E(): 0, 100.0% identity in 349 aa overlap. Contains PS00893 mutT domain signature. | 0.621 |
| ML0450 | ML0452 | gene:17574271 | gene:17574273 | Putative pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Putative glycosyltransferase; Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM). Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1); Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | 0.668 |
| ML0450 | ML0453 | gene:17574271 | gene:17574274 | Putative pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Similar to M. tuberculosis Rv2611c, conserved hypothetical protein, TR:O06203 (EMBL:AL123456) (316 aa); Fasta score E(): 0, 71.5% identity in 312 aa overlap. Shows weak similarity to putative acyltransferases e.g. Campylobacter jejuni lipid A biosynthesis acyltransferase, TR:AAF31766 (EMBL:AF130984) (295 aa); Fasta score E(): 0.00017, 20.0% identity in 180 aa overlap. previously sequenced as TR:O07148 (EMBL:Z96801) (320 aa); Fasta score E(): 0, 99.7% identity in 320 aa overlap. | 0.620 |
| ML0450 | ML0455 | gene:17574271 | gene:17574276 | Putative pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Similar to M. tuberculosis Rv2613c, conserved hypothetical protein, TR:O06201 (EMBL:AL123456) (195 aa); Fasta score E(): 0, 84.7% identity in 196 aa overlap. Similar to many HIT-family hypothetical proteins. Previously sequenced as TR:O07150 (EMBL:Z96801) (186 aa); Fasta score E(): 0, 100.0% identity in 186 aa overlap. Contains Pfam match to entry PF01230 HIT, HIT family. | 0.756 |
| ML0450 | pgsA | gene:17574271 | gene:17574275 | Putative pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Similar to M. tuberculosis pgsA, Rv2612c, putative CDP-alcohol phosphatidyltransferases, TR:O06202 (EMBL:AL123456) (217 aa); Fasta score E(): 0, 79.3% identity in 213 aa overlap. Shows weak similarity to Escherichia coli pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, SW:PGSA_ECOLI (P06978) (738 aa); BlastP Expect 8.6. Previously sequenced as TR:O07149 (EMBL:Z96801) (239 aa); Fasta score E(): 0, 100.0% identity in 239 aa overlap. Contains Pfam match to entry PF01066 CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase. Contains PS00379 CDP-alcohol phosphatidyl [...] | 0.648 |
| ML0450 | thrS | gene:17574271 | gene:17574277 | Putative pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | 0.759 |
| ML0451 | ML0450 | gene:17574272 | gene:17574271 | Similar to M. tuberculosis Rv2609c, conserved hypothetical protein, TR:O06205 (EMBL:AL123456) (351 aa); Fasta score E(): 0, 77.7% identity in 336 aa overlap. Similar, in part, to hypothetical proteins from Streptomyces coelicolor e.g. SC2E1.17, hypothetical protein, TR:O69888 (EMBL:AL023797) (172 aa); Fasta score E(): 2e-13, 43.3% identity in 150 aa overlap. Previously sequenced as TR:O07146 (EMBL:Z96801) (349 aa); Fasta score E(): 0, 100.0% identity in 349 aa overlap. Contains PS00893 mutT domain signature. | Putative pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.621 |
| ML0451 | ML0452 | gene:17574272 | gene:17574273 | Similar to M. tuberculosis Rv2609c, conserved hypothetical protein, TR:O06205 (EMBL:AL123456) (351 aa); Fasta score E(): 0, 77.7% identity in 336 aa overlap. Similar, in part, to hypothetical proteins from Streptomyces coelicolor e.g. SC2E1.17, hypothetical protein, TR:O69888 (EMBL:AL023797) (172 aa); Fasta score E(): 2e-13, 43.3% identity in 150 aa overlap. Previously sequenced as TR:O07146 (EMBL:Z96801) (349 aa); Fasta score E(): 0, 100.0% identity in 349 aa overlap. Contains PS00893 mutT domain signature. | Putative glycosyltransferase; Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM). Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1); Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | 0.939 |
| ML0451 | ML0453 | gene:17574272 | gene:17574274 | Similar to M. tuberculosis Rv2609c, conserved hypothetical protein, TR:O06205 (EMBL:AL123456) (351 aa); Fasta score E(): 0, 77.7% identity in 336 aa overlap. Similar, in part, to hypothetical proteins from Streptomyces coelicolor e.g. SC2E1.17, hypothetical protein, TR:O69888 (EMBL:AL023797) (172 aa); Fasta score E(): 2e-13, 43.3% identity in 150 aa overlap. Previously sequenced as TR:O07146 (EMBL:Z96801) (349 aa); Fasta score E(): 0, 100.0% identity in 349 aa overlap. Contains PS00893 mutT domain signature. | Similar to M. tuberculosis Rv2611c, conserved hypothetical protein, TR:O06203 (EMBL:AL123456) (316 aa); Fasta score E(): 0, 71.5% identity in 312 aa overlap. Shows weak similarity to putative acyltransferases e.g. Campylobacter jejuni lipid A biosynthesis acyltransferase, TR:AAF31766 (EMBL:AF130984) (295 aa); Fasta score E(): 0.00017, 20.0% identity in 180 aa overlap. previously sequenced as TR:O07148 (EMBL:Z96801) (320 aa); Fasta score E(): 0, 99.7% identity in 320 aa overlap. | 0.932 |
| ML0451 | ML0455 | gene:17574272 | gene:17574276 | Similar to M. tuberculosis Rv2609c, conserved hypothetical protein, TR:O06205 (EMBL:AL123456) (351 aa); Fasta score E(): 0, 77.7% identity in 336 aa overlap. Similar, in part, to hypothetical proteins from Streptomyces coelicolor e.g. SC2E1.17, hypothetical protein, TR:O69888 (EMBL:AL023797) (172 aa); Fasta score E(): 2e-13, 43.3% identity in 150 aa overlap. Previously sequenced as TR:O07146 (EMBL:Z96801) (349 aa); Fasta score E(): 0, 100.0% identity in 349 aa overlap. Contains PS00893 mutT domain signature. | Similar to M. tuberculosis Rv2613c, conserved hypothetical protein, TR:O06201 (EMBL:AL123456) (195 aa); Fasta score E(): 0, 84.7% identity in 196 aa overlap. Similar to many HIT-family hypothetical proteins. Previously sequenced as TR:O07150 (EMBL:Z96801) (186 aa); Fasta score E(): 0, 100.0% identity in 186 aa overlap. Contains Pfam match to entry PF01230 HIT, HIT family. | 0.859 |
| ML0451 | ML2297 | gene:17574272 | gene:17576157 | Similar to M. tuberculosis Rv2609c, conserved hypothetical protein, TR:O06205 (EMBL:AL123456) (351 aa); Fasta score E(): 0, 77.7% identity in 336 aa overlap. Similar, in part, to hypothetical proteins from Streptomyces coelicolor e.g. SC2E1.17, hypothetical protein, TR:O69888 (EMBL:AL023797) (172 aa); Fasta score E(): 2e-13, 43.3% identity in 150 aa overlap. Previously sequenced as TR:O07146 (EMBL:Z96801) (349 aa); Fasta score E(): 0, 100.0% identity in 349 aa overlap. Contains PS00893 mutT domain signature. | Putative hydrolase; Similar to Mycobacterium tuberculosis putative epoxide hydrolase Rv3670 or MTV025.018 TR:O69638 (EMBL:AL022121) (327 aa) fasta scores: E(): 0, 80.6% id in 324 aa. Similar many putative hydrolases and shows weak similarity to Homo sapiens soluble epoxide hydrolase ephX2 SW:HYES_HUMAN (P34913) (554 aa) fasta scores: E(): 3.1e-12, 28.1% id in 285 aa. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. | 0.403 |
| ML0451 | pgsA | gene:17574272 | gene:17574275 | Similar to M. tuberculosis Rv2609c, conserved hypothetical protein, TR:O06205 (EMBL:AL123456) (351 aa); Fasta score E(): 0, 77.7% identity in 336 aa overlap. Similar, in part, to hypothetical proteins from Streptomyces coelicolor e.g. SC2E1.17, hypothetical protein, TR:O69888 (EMBL:AL023797) (172 aa); Fasta score E(): 2e-13, 43.3% identity in 150 aa overlap. Previously sequenced as TR:O07146 (EMBL:Z96801) (349 aa); Fasta score E(): 0, 100.0% identity in 349 aa overlap. Contains PS00893 mutT domain signature. | Similar to M. tuberculosis pgsA, Rv2612c, putative CDP-alcohol phosphatidyltransferases, TR:O06202 (EMBL:AL123456) (217 aa); Fasta score E(): 0, 79.3% identity in 213 aa overlap. Shows weak similarity to Escherichia coli pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, SW:PGSA_ECOLI (P06978) (738 aa); BlastP Expect 8.6. Previously sequenced as TR:O07149 (EMBL:Z96801) (239 aa); Fasta score E(): 0, 100.0% identity in 239 aa overlap. Contains Pfam match to entry PF01066 CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase. Contains PS00379 CDP-alcohol phosphatidyl [...] | 0.859 |
| ML0451 | thrS | gene:17574272 | gene:17574277 | Similar to M. tuberculosis Rv2609c, conserved hypothetical protein, TR:O06205 (EMBL:AL123456) (351 aa); Fasta score E(): 0, 77.7% identity in 336 aa overlap. Similar, in part, to hypothetical proteins from Streptomyces coelicolor e.g. SC2E1.17, hypothetical protein, TR:O69888 (EMBL:AL023797) (172 aa); Fasta score E(): 2e-13, 43.3% identity in 150 aa overlap. Previously sequenced as TR:O07146 (EMBL:Z96801) (349 aa); Fasta score E(): 0, 100.0% identity in 349 aa overlap. Contains PS00893 mutT domain signature. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | 0.859 |
| ML0452 | ML0450 | gene:17574273 | gene:17574271 | Putative glycosyltransferase; Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM). Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1); Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | Putative pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.668 |
| ML0452 | ML0451 | gene:17574273 | gene:17574272 | Putative glycosyltransferase; Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM). Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1); Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | Similar to M. tuberculosis Rv2609c, conserved hypothetical protein, TR:O06205 (EMBL:AL123456) (351 aa); Fasta score E(): 0, 77.7% identity in 336 aa overlap. Similar, in part, to hypothetical proteins from Streptomyces coelicolor e.g. SC2E1.17, hypothetical protein, TR:O69888 (EMBL:AL023797) (172 aa); Fasta score E(): 2e-13, 43.3% identity in 150 aa overlap. Previously sequenced as TR:O07146 (EMBL:Z96801) (349 aa); Fasta score E(): 0, 100.0% identity in 349 aa overlap. Contains PS00893 mutT domain signature. | 0.939 |
| ML0452 | ML0453 | gene:17574273 | gene:17574274 | Putative glycosyltransferase; Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM). Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1); Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | Similar to M. tuberculosis Rv2611c, conserved hypothetical protein, TR:O06203 (EMBL:AL123456) (316 aa); Fasta score E(): 0, 71.5% identity in 312 aa overlap. Shows weak similarity to putative acyltransferases e.g. Campylobacter jejuni lipid A biosynthesis acyltransferase, TR:AAF31766 (EMBL:AF130984) (295 aa); Fasta score E(): 0.00017, 20.0% identity in 180 aa overlap. previously sequenced as TR:O07148 (EMBL:Z96801) (320 aa); Fasta score E(): 0, 99.7% identity in 320 aa overlap. | 0.999 |
| ML0452 | ML0455 | gene:17574273 | gene:17574276 | Putative glycosyltransferase; Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM). Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1); Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | Similar to M. tuberculosis Rv2613c, conserved hypothetical protein, TR:O06201 (EMBL:AL123456) (195 aa); Fasta score E(): 0, 84.7% identity in 196 aa overlap. Similar to many HIT-family hypothetical proteins. Previously sequenced as TR:O07150 (EMBL:Z96801) (186 aa); Fasta score E(): 0, 100.0% identity in 186 aa overlap. Contains Pfam match to entry PF01230 HIT, HIT family. | 0.900 |
| ML0452 | ML0886 | gene:17574273 | gene:17574712 | Putative glycosyltransferase; Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM). Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1); Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | Possible glycosyl transferase; Previously sequenced Mycobacterium leprae hypothetical protein TR:O69579 (EMBL:AL022602) (384 aa); Fasta score E(): 0, 99.7% identity in 384 aa overlap(EMBL:AL022602). Also similar to Mycobacterium tuberculosis hypothetical protein TR:O53522 (EMBL:AL021957) (399 aa); Fasta score E(): 0, 81.5% identity in 383 aa overlap(EMBL:AL021957) and several Streptomyces coelicolor putative glycosyl transferases e.g. TR:Q9X7Z1 (EMBL:AL049497) (412 aa); Fasta score E(): 0, 52.2% identity in 387 aa overlap(EMBL:AL049497). Contains Pfam match to entry PF00534 Glycos_tran [...] | 0.932 |
| ML0452 | ML1312 | gene:17574273 | gene:17575146 | Putative glycosyltransferase; Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM). Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1); Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | Conserved hypothetical protein; Highly similar to several proteins of unknown function e.g. Mycobacterium tuberculosis RV2119 TR:O33254 (EMBL:Z97559) (278 aa); Fasta score E(): 0, 79.9% identity in 278 aa overlap. | 0.514 |
| ML0452 | ML2297 | gene:17574273 | gene:17576157 | Putative glycosyltransferase; Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM). Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1); Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | Putative hydrolase; Similar to Mycobacterium tuberculosis putative epoxide hydrolase Rv3670 or MTV025.018 TR:O69638 (EMBL:AL022121) (327 aa) fasta scores: E(): 0, 80.6% id in 324 aa. Similar many putative hydrolases and shows weak similarity to Homo sapiens soluble epoxide hydrolase ephX2 SW:HYES_HUMAN (P34913) (554 aa) fasta scores: E(): 3.1e-12, 28.1% id in 285 aa. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. | 0.522 |
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