Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ML0201 | ndk | gene:17574017 | gene:17575307 | Putative membrane protein; Similar to M. tuberculosis Rv3645, probable transmembrane protein, TR:O06362 (EMBL:AL123456) (549 aa); Fasta score E(): 0, 85.3% identity in 530 aa overlap and to several other putative membrane proteins from M. tuberculosis. Shares regions of similarity with adenylate cyclases e.g. Anabaena sp. (strain PCC 7120) cyaA, adenylate cyclase, TR:P94180 (EMBL:D89622) (735 aa); Fasta score E(): 1.5e-16, 33.3% identity in 228 aa overlap. Previously sequenced as TR:O69547 (EMBL:AL023093) (530 aa); Fasta score E(): 0, 99.8% identity in 530 aa overlap. Contains hydropho [...] | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
| ML0201 | pykA | gene:17574017 | gene:17575109 | Putative membrane protein; Similar to M. tuberculosis Rv3645, probable transmembrane protein, TR:O06362 (EMBL:AL123456) (549 aa); Fasta score E(): 0, 85.3% identity in 530 aa overlap and to several other putative membrane proteins from M. tuberculosis. Shares regions of similarity with adenylate cyclases e.g. Anabaena sp. (strain PCC 7120) cyaA, adenylate cyclase, TR:P94180 (EMBL:D89622) (735 aa); Fasta score E(): 1.5e-16, 33.3% identity in 228 aa overlap. Previously sequenced as TR:O69547 (EMBL:AL023093) (530 aa); Fasta score E(): 0, 99.8% identity in 530 aa overlap. Contains hydropho [...] | Pyruvate kinase; Highly similar to many pyruvate kinases (EC 2.7.1.40) including: Mycobacterium tuberculosis RV1617 SW:KPYK_MYCTU (O06134) (472 aa); Fasta score E(): 0, 90.7% identity in 472 aa overlap and Corynebacterium glutamicum SW:KPYK_CORGL (Q46078) (475 aa); Fasta score E(): 0, 71.8% identity in 468 aa overlap. Contains Pfam match to entry PF00224 PK, Pyruvate kinase. Contains PS00110 Pyruvate kinase active site signature. | 0.903 |
| ML0201 | relA | gene:17574017 | gene:17574312 | Putative membrane protein; Similar to M. tuberculosis Rv3645, probable transmembrane protein, TR:O06362 (EMBL:AL123456) (549 aa); Fasta score E(): 0, 85.3% identity in 530 aa overlap and to several other putative membrane proteins from M. tuberculosis. Shares regions of similarity with adenylate cyclases e.g. Anabaena sp. (strain PCC 7120) cyaA, adenylate cyclase, TR:P94180 (EMBL:D89622) (735 aa); Fasta score E(): 1.5e-16, 33.3% identity in 228 aa overlap. Previously sequenced as TR:O69547 (EMBL:AL023093) (530 aa); Fasta score E(): 0, 99.8% identity in 530 aa overlap. Contains hydropho [...] | Putative GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 0.900 |
| ML0258 | ML2434 | gene:17574076 | gene:17576297 | Hypothetical protein; Similar to M. tuberculosis Rv1026, hypothetical protein, TR:P96374 (EMBL:AL123456) (319 aa); Fasta score E(): 0, 77.6% identity in 321 aa overlap. Similar to many bacterial hypothetical proteins and shows weak similarity to N-terminal half of Escherichia coli ppx, exopolyphosphatase, SW:PPX_ECOLI (P29014) (512 aa); Fasta score E(): 6.8e-07, 25.3% identity in 297 aa overlap; Shows weak similarity to ML2434. | Conserved hypothetical protein; Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain. | 0.980 |
| ML0258 | relA | gene:17574076 | gene:17574312 | Hypothetical protein; Similar to M. tuberculosis Rv1026, hypothetical protein, TR:P96374 (EMBL:AL123456) (319 aa); Fasta score E(): 0, 77.6% identity in 321 aa overlap. Similar to many bacterial hypothetical proteins and shows weak similarity to N-terminal half of Escherichia coli ppx, exopolyphosphatase, SW:PPX_ECOLI (P29014) (512 aa); Fasta score E(): 6.8e-07, 25.3% identity in 297 aa overlap; Shows weak similarity to ML2434. | Putative GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 0.909 |
| ML2434 | ML0258 | gene:17576297 | gene:17574076 | Conserved hypothetical protein; Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain. | Hypothetical protein; Similar to M. tuberculosis Rv1026, hypothetical protein, TR:P96374 (EMBL:AL123456) (319 aa); Fasta score E(): 0, 77.6% identity in 321 aa overlap. Similar to many bacterial hypothetical proteins and shows weak similarity to N-terminal half of Escherichia coli ppx, exopolyphosphatase, SW:PPX_ECOLI (P29014) (512 aa); Fasta score E(): 6.8e-07, 25.3% identity in 297 aa overlap; Shows weak similarity to ML2434. | 0.980 |
| ML2434 | relA | gene:17576297 | gene:17574312 | Conserved hypothetical protein; Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain. | Putative GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 0.909 |
| gmk | ndk | gene:17574362 | gene:17575307 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.931 |
| gmk | nrdE | gene:17574362 | gene:17575579 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside diphosphate reductase [alpha] chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | 0.907 |
| gmk | nrdF | gene:17574362 | gene:17575576 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleotide reductase small subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | 0.904 |
| gmk | pykA | gene:17574362 | gene:17575109 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase; Highly similar to many pyruvate kinases (EC 2.7.1.40) including: Mycobacterium tuberculosis RV1617 SW:KPYK_MYCTU (O06134) (472 aa); Fasta score E(): 0, 90.7% identity in 472 aa overlap and Corynebacterium glutamicum SW:KPYK_CORGL (Q46078) (475 aa); Fasta score E(): 0, 71.8% identity in 468 aa overlap. Contains Pfam match to entry PF00224 PK, Pyruvate kinase. Contains PS00110 Pyruvate kinase active site signature. | 0.912 |
| gmk | relA | gene:17574362 | gene:17574312 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 0.913 |
| ndk | ML0201 | gene:17575307 | gene:17574017 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Putative membrane protein; Similar to M. tuberculosis Rv3645, probable transmembrane protein, TR:O06362 (EMBL:AL123456) (549 aa); Fasta score E(): 0, 85.3% identity in 530 aa overlap and to several other putative membrane proteins from M. tuberculosis. Shares regions of similarity with adenylate cyclases e.g. Anabaena sp. (strain PCC 7120) cyaA, adenylate cyclase, TR:P94180 (EMBL:D89622) (735 aa); Fasta score E(): 1.5e-16, 33.3% identity in 228 aa overlap. Previously sequenced as TR:O69547 (EMBL:AL023093) (530 aa); Fasta score E(): 0, 99.8% identity in 530 aa overlap. Contains hydropho [...] | 0.900 |
| ndk | gmk | gene:17575307 | gene:17574362 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.931 |
| ndk | nrdE | gene:17575307 | gene:17575579 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleoside diphosphate reductase [alpha] chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | 0.911 |
| ndk | nrdF | gene:17575307 | gene:17575576 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleotide reductase small subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | 0.908 |
| ndk | pykA | gene:17575307 | gene:17575109 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Pyruvate kinase; Highly similar to many pyruvate kinases (EC 2.7.1.40) including: Mycobacterium tuberculosis RV1617 SW:KPYK_MYCTU (O06134) (472 aa); Fasta score E(): 0, 90.7% identity in 472 aa overlap and Corynebacterium glutamicum SW:KPYK_CORGL (Q46078) (475 aa); Fasta score E(): 0, 71.8% identity in 468 aa overlap. Contains Pfam match to entry PF00224 PK, Pyruvate kinase. Contains PS00110 Pyruvate kinase active site signature. | 0.905 |
| ndk | relA | gene:17575307 | gene:17574312 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Putative GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 0.909 |
| ndk | rplF | gene:17575307 | gene:17575692 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.640 |
| ndk | rplM | gene:17575307 | gene:17574183 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.846 |
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