node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ML0573 | ML0574 | gene:17574394 | gene:17574395 | Hypothetical protein; Unknown function. Previously sequenced as TR:Q49684 (EMBL:U00013) (91 aa); Fasta score E(): 0, 98.9% identity in 91 aa overlap. Contains Pfam match to entry PF00121 TIM, Triosephosphate isomerase. | Hypothetical protein; Unknown function. Previously sequenced as TR:Q49680 (EMBL:U00013) (105 aa); Fasta score E(): 0, 99.0% identity in 105 aa overlap. | 0.773 |
ML0573 | gap | gene:17574394 | gene:17574391 | Hypothetical protein; Unknown function. Previously sequenced as TR:Q49684 (EMBL:U00013) (91 aa); Fasta score E(): 0, 98.9% identity in 91 aa overlap. Contains Pfam match to entry PF00121 TIM, Triosephosphate isomerase. | Glyceraldehyde 3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. | 0.773 |
ML0573 | pgk | gene:17574394 | gene:17574392 | Hypothetical protein; Unknown function. Previously sequenced as TR:Q49684 (EMBL:U00013) (91 aa); Fasta score E(): 0, 98.9% identity in 91 aa overlap. Contains Pfam match to entry PF00121 TIM, Triosephosphate isomerase. | Phosphoglycerate kinase; Similar to M. tuberculosis pgk, Rv1437, phosphoglycerate kinase, SW:PGK_MYCTU (O06821) (412 aa); Fasta score E(): 0, 80.6% identity in 412 aa overlap. Similar to many e.g. Corynebacterium glutamicum pgk, phosphoglycerate kinase, SW:PGK_CORGL (Q01655) (403 aa); Fasta score E(): 0, 59.2% identity in 407 aa overlap. Previously sequenced as SW:PGK_MYCLE (P46712) (416 aa); Fasta score E(): 0, 99.8% identity in 416 aa overlap. Contains Pfam match to entry PF00162 PGK, Phosphoglycerate kinases. Contains PS00111 Phosphoglycerate kinase signature. | 0.773 |
ML0573 | tpi | gene:17574394 | gene:17574393 | Hypothetical protein; Unknown function. Previously sequenced as TR:Q49684 (EMBL:U00013) (91 aa); Fasta score E(): 0, 98.9% identity in 91 aa overlap. Contains Pfam match to entry PF00121 TIM, Triosephosphate isomerase. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.773 |
ML0574 | ML0573 | gene:17574395 | gene:17574394 | Hypothetical protein; Unknown function. Previously sequenced as TR:Q49680 (EMBL:U00013) (105 aa); Fasta score E(): 0, 99.0% identity in 105 aa overlap. | Hypothetical protein; Unknown function. Previously sequenced as TR:Q49684 (EMBL:U00013) (91 aa); Fasta score E(): 0, 98.9% identity in 91 aa overlap. Contains Pfam match to entry PF00121 TIM, Triosephosphate isomerase. | 0.773 |
ML0574 | gap | gene:17574395 | gene:17574391 | Hypothetical protein; Unknown function. Previously sequenced as TR:Q49680 (EMBL:U00013) (105 aa); Fasta score E(): 0, 99.0% identity in 105 aa overlap. | Glyceraldehyde 3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. | 0.773 |
ML0574 | pgk | gene:17574395 | gene:17574392 | Hypothetical protein; Unknown function. Previously sequenced as TR:Q49680 (EMBL:U00013) (105 aa); Fasta score E(): 0, 99.0% identity in 105 aa overlap. | Phosphoglycerate kinase; Similar to M. tuberculosis pgk, Rv1437, phosphoglycerate kinase, SW:PGK_MYCTU (O06821) (412 aa); Fasta score E(): 0, 80.6% identity in 412 aa overlap. Similar to many e.g. Corynebacterium glutamicum pgk, phosphoglycerate kinase, SW:PGK_CORGL (Q01655) (403 aa); Fasta score E(): 0, 59.2% identity in 407 aa overlap. Previously sequenced as SW:PGK_MYCLE (P46712) (416 aa); Fasta score E(): 0, 99.8% identity in 416 aa overlap. Contains Pfam match to entry PF00162 PGK, Phosphoglycerate kinases. Contains PS00111 Phosphoglycerate kinase signature. | 0.773 |
ML0574 | tpi | gene:17574395 | gene:17574393 | Hypothetical protein; Unknown function. Previously sequenced as TR:Q49680 (EMBL:U00013) (105 aa); Fasta score E(): 0, 99.0% identity in 105 aa overlap. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.773 |
eno | fba | gene:17574073 | gene:17574105 | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Putative fructose bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.964 |
eno | gap | gene:17574073 | gene:17574391 | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glyceraldehyde 3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. | 0.965 |
eno | gpm | gene:17574073 | gene:17576304 | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.975 |
eno | pgi | gene:17574073 | gene:17573965 | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glucose-6-phosphate isomerase; Similar to M. tuberculosis Rv0946c, pgi, glucose-6-phosphate isomerase, SW:G6PI_MYCTU (P77895) (553 aa); Fasta score E(): 0, 85.5% identity in 552 aa overlap and Mycobacterium smegmatis pgi, glucose-6-phosphate isomerase, SW:G6PI_MYCSM (P96803) (442 aa); Fasta score E(): 0, 84.1% identity in 440 aa overlap. Contains Pfam match to entry PF00342 PGI, Phosphoglucose isomerase. Contains PS00765 Phosphoglucose isomerase signature 1. Contains PS00174 Phosphoglucose isomerase signature 2. | 0.979 |
eno | pgk | gene:17574073 | gene:17574392 | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoglycerate kinase; Similar to M. tuberculosis pgk, Rv1437, phosphoglycerate kinase, SW:PGK_MYCTU (O06821) (412 aa); Fasta score E(): 0, 80.6% identity in 412 aa overlap. Similar to many e.g. Corynebacterium glutamicum pgk, phosphoglycerate kinase, SW:PGK_CORGL (Q01655) (403 aa); Fasta score E(): 0, 59.2% identity in 407 aa overlap. Previously sequenced as SW:PGK_MYCLE (P46712) (416 aa); Fasta score E(): 0, 99.8% identity in 416 aa overlap. Contains Pfam match to entry PF00162 PGK, Phosphoglycerate kinases. Contains PS00111 Phosphoglycerate kinase signature. | 0.986 |
eno | pykA | gene:17574073 | gene:17575109 | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Pyruvate kinase; Highly similar to many pyruvate kinases (EC 2.7.1.40) including: Mycobacterium tuberculosis RV1617 SW:KPYK_MYCTU (O06134) (472 aa); Fasta score E(): 0, 90.7% identity in 472 aa overlap and Corynebacterium glutamicum SW:KPYK_CORGL (Q46078) (475 aa); Fasta score E(): 0, 71.8% identity in 468 aa overlap. Contains Pfam match to entry PF00224 PK, Pyruvate kinase. Contains PS00110 Pyruvate kinase active site signature. | 0.992 |
eno | tkt | gene:17574073 | gene:17574404 | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.926 |
eno | tpi | gene:17574073 | gene:17574393 | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.956 |
fba | eno | gene:17574105 | gene:17574073 | Putative fructose bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.964 |
fba | gap | gene:17574105 | gene:17574391 | Putative fructose bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glyceraldehyde 3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. | 0.982 |
fba | gpm | gene:17574105 | gene:17576304 | Putative fructose bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.913 |
fba | pgi | gene:17574105 | gene:17573965 | Putative fructose bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glucose-6-phosphate isomerase; Similar to M. tuberculosis Rv0946c, pgi, glucose-6-phosphate isomerase, SW:G6PI_MYCTU (P77895) (553 aa); Fasta score E(): 0, 85.5% identity in 552 aa overlap and Mycobacterium smegmatis pgi, glucose-6-phosphate isomerase, SW:G6PI_MYCSM (P96803) (442 aa); Fasta score E(): 0, 84.1% identity in 440 aa overlap. Contains Pfam match to entry PF00342 PGI, Phosphoglucose isomerase. Contains PS00765 Phosphoglucose isomerase signature 1. Contains PS00174 Phosphoglucose isomerase signature 2. | 0.960 |