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murE protein (Mycobacterium leprae) - STRING interaction network
"murE" - UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase in Mycobacterium leprae
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (530 aa)    
Predicted Functional Partners:
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase (D-alanine-D-alanine-adding enzyme); Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (517 aa)
  0.999
murD
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (490 aa)
 
 
  0.999
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation (495 aa)
 
 
  0.997
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (407 aa)
 
 
  0.996
ftsW
Cell division protein FtsW (534 aa)
 
 
  0.993
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (359 aa)
 
   
  0.985
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (296 aa)
 
 
  0.974
pbpB
Penicillin-binding protein 2 (675 aa)
   
  0.965
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation (367 aa)
 
 
  0.947
ftsQ
Cell division protein FtsQ; Essential cell division protein (341 aa)
   
   
  0.944
Your Current Organism:
Mycobacterium leprae
NCBI taxonomy Id: 272631
Other names: Bacillus leprae, M. leprae, M. leprae TN, Mycobacterium leprae, Mycobacterium leprae TN, Mycobacterium leprae str. TN, Mycobacterium leprae strain TN, Mycoplasma leprae
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