node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ML0989 | ML0997 | gene:17574815 | gene:17574823 | Conserved hypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Possible ATP/GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.448 |
ML0989 | ML1061 | gene:17574815 | gene:17574887 | Conserved hypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49952 (EMBL:U15180) (187 aa); Fasta score E(): 0, 100.0% identity in 187 aa overlap. Also highly similar to Mycobacterium tuberculosis TR:O05306 (EMBL:Z93777) (187 aa); Fasta score E(): 0, 72.4% identity in 174 aa overlap; Belongs to the LOG family. | 0.731 |
ML0989 | dapF | gene:17574815 | gene:17574822 | Conserved hypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.460 |
ML0989 | miaA | gene:17574815 | gene:17574821 | Conserved hypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | tRNA [delta](2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.935 |
ML0994 | ML0997 | gene:17574820 | gene:17574823 | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49835 (EMBL:U00019) (232 aa); Fasta score E(): 0, 99.6% identity in 232 aa overlap. Also highly similar to proteins of undefined function from Mycobacterium tuberculosis Rv2728c TR:O33233 (EMBL:Z98209) (231 aa); Fasta score E(): 0, 68.5% identity in 232 aa overlap and Streptomyces coelicolor TR:O69964 (EMBL:AL022268) (237 aa); Fasta score E(): 1.3e-13, 32.9% identity in 243 aa overlap. | Possible ATP/GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.524 |
ML0994 | dapF | gene:17574820 | gene:17574822 | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49835 (EMBL:U00019) (232 aa); Fasta score E(): 0, 99.6% identity in 232 aa overlap. Also highly similar to proteins of undefined function from Mycobacterium tuberculosis Rv2728c TR:O33233 (EMBL:Z98209) (231 aa); Fasta score E(): 0, 68.5% identity in 232 aa overlap and Streptomyces coelicolor TR:O69964 (EMBL:AL022268) (237 aa); Fasta score E(): 1.3e-13, 32.9% identity in 243 aa overlap. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.762 |
ML0994 | miaA | gene:17574820 | gene:17574821 | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49835 (EMBL:U00019) (232 aa); Fasta score E(): 0, 99.6% identity in 232 aa overlap. Also highly similar to proteins of undefined function from Mycobacterium tuberculosis Rv2728c TR:O33233 (EMBL:Z98209) (231 aa); Fasta score E(): 0, 68.5% identity in 232 aa overlap and Streptomyces coelicolor TR:O69964 (EMBL:AL022268) (237 aa); Fasta score E(): 1.3e-13, 32.9% identity in 243 aa overlap. | tRNA [delta](2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.859 |
ML0997 | ML0989 | gene:17574823 | gene:17574815 | Possible ATP/GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Conserved hypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.448 |
ML0997 | ML0994 | gene:17574823 | gene:17574820 | Possible ATP/GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49835 (EMBL:U00019) (232 aa); Fasta score E(): 0, 99.6% identity in 232 aa overlap. Also highly similar to proteins of undefined function from Mycobacterium tuberculosis Rv2728c TR:O33233 (EMBL:Z98209) (231 aa); Fasta score E(): 0, 68.5% identity in 232 aa overlap and Streptomyces coelicolor TR:O69964 (EMBL:AL022268) (237 aa); Fasta score E(): 1.3e-13, 32.9% identity in 243 aa overlap. | 0.524 |
ML0997 | dapF | gene:17574823 | gene:17574822 | Possible ATP/GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.873 |
ML0997 | miaA | gene:17574823 | gene:17574821 | Possible ATP/GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | tRNA [delta](2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.750 |
ML0997 | rplI | gene:17574823 | gene:17576548 | Possible ATP/GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 50S ribosomal protein L9; Binds to the 23S rRNA. | 0.774 |
ML0997 | rplY | gene:17574823 | gene:17574062 | Possible ATP/GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Putative 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.475 |
ML1061 | ML0989 | gene:17574887 | gene:17574815 | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49952 (EMBL:U15180) (187 aa); Fasta score E(): 0, 100.0% identity in 187 aa overlap. Also highly similar to Mycobacterium tuberculosis TR:O05306 (EMBL:Z93777) (187 aa); Fasta score E(): 0, 72.4% identity in 174 aa overlap; Belongs to the LOG family. | Conserved hypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.731 |
ML1061 | miaA | gene:17574887 | gene:17574821 | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49952 (EMBL:U15180) (187 aa); Fasta score E(): 0, 100.0% identity in 187 aa overlap. Also highly similar to Mycobacterium tuberculosis TR:O05306 (EMBL:Z93777) (187 aa); Fasta score E(): 0, 72.4% identity in 174 aa overlap; Belongs to the LOG family. | tRNA [delta](2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.767 |
dapF | ML0989 | gene:17574822 | gene:17574815 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Conserved hypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.460 |
dapF | ML0994 | gene:17574822 | gene:17574820 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49835 (EMBL:U00019) (232 aa); Fasta score E(): 0, 99.6% identity in 232 aa overlap. Also highly similar to proteins of undefined function from Mycobacterium tuberculosis Rv2728c TR:O33233 (EMBL:Z98209) (231 aa); Fasta score E(): 0, 68.5% identity in 232 aa overlap and Streptomyces coelicolor TR:O69964 (EMBL:AL022268) (237 aa); Fasta score E(): 1.3e-13, 32.9% identity in 243 aa overlap. | 0.762 |
dapF | ML0997 | gene:17574822 | gene:17574823 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Possible ATP/GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.873 |
dapF | miaA | gene:17574822 | gene:17574821 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | tRNA [delta](2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.762 |
dapF | ribG | gene:17574822 | gene:17574376 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Putative bifunctional riboflavin-specific deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.486 |