node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ML1005 | ML1149 | gene:17574831 | gene:17574976 | Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD14_MYCLE (P53523) (191 aa); Fasta score E(): 0, 100.0% identity in 191 aa overlap. Also similar to many other proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv1314c SW:YD14_MYCTU (Q10622) (193 aa); Fasta score E(): 0, 81.2% identity in 191 aa overlap. Contains Pfam match to entry PF01923 DUF80, Protein of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.691 |
ML1005 | ML2084 | gene:17574831 | gene:17575936 | Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Probable multidrug resistance pump; Similar to Mycobacterium tuberculosis hypothetical ABC transporter ATP-binding protein Rv1819c SW:YI19_MYCTU (Q50614) fasta scores: E(): 0, 74.9% in 634 aa, and in C-term to Escherichia coli hypothetical ABC transporter ATP-binding protein in pqql-hipa intergenic region SW:YDDA_ECOLI (P31826; P76133; P76876) fasta scores: E(): 0, 29.9% in 551 aa. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature; Similar to ML1089, ML1424, ML0848 a [...] | 0.550 |
ML1005 | cobT | gene:17574831 | gene:17574694 | Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Putative nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.684 |
ML1148 | ML1149 | gene:17574975 | gene:17574976 | Doubtful CDS; Identical to the previously sequenced Mycobacterium leprae TR:Q50137 (EMBL:U15186) (51 aa); Fasta score E(): 4.9e-22, 100.0% identity in 51 aa overlap. | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD14_MYCLE (P53523) (191 aa); Fasta score E(): 0, 100.0% identity in 191 aa overlap. Also similar to many other proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv1314c SW:YD14_MYCTU (Q10622) (193 aa); Fasta score E(): 0, 81.2% identity in 191 aa overlap. Contains Pfam match to entry PF01923 DUF80, Protein of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.438 |
ML1149 | ML1005 | gene:17574976 | gene:17574831 | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD14_MYCLE (P53523) (191 aa); Fasta score E(): 0, 100.0% identity in 191 aa overlap. Also similar to many other proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv1314c SW:YD14_MYCTU (Q10622) (193 aa); Fasta score E(): 0, 81.2% identity in 191 aa overlap. Contains Pfam match to entry PF01923 DUF80, Protein of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.691 |
ML1149 | ML1148 | gene:17574976 | gene:17574975 | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD14_MYCLE (P53523) (191 aa); Fasta score E(): 0, 100.0% identity in 191 aa overlap. Also similar to many other proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv1314c SW:YD14_MYCTU (Q10622) (193 aa); Fasta score E(): 0, 81.2% identity in 191 aa overlap. Contains Pfam match to entry PF01923 DUF80, Protein of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | Doubtful CDS; Identical to the previously sequenced Mycobacterium leprae TR:Q50137 (EMBL:U15186) (51 aa); Fasta score E(): 4.9e-22, 100.0% identity in 51 aa overlap. | 0.438 |
ML1149 | ML2084 | gene:17574976 | gene:17575936 | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD14_MYCLE (P53523) (191 aa); Fasta score E(): 0, 100.0% identity in 191 aa overlap. Also similar to many other proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv1314c SW:YD14_MYCTU (Q10622) (193 aa); Fasta score E(): 0, 81.2% identity in 191 aa overlap. Contains Pfam match to entry PF01923 DUF80, Protein of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | Probable multidrug resistance pump; Similar to Mycobacterium tuberculosis hypothetical ABC transporter ATP-binding protein Rv1819c SW:YI19_MYCTU (Q50614) fasta scores: E(): 0, 74.9% in 634 aa, and in C-term to Escherichia coli hypothetical ABC transporter ATP-binding protein in pqql-hipa intergenic region SW:YDDA_ECOLI (P31826; P76133; P76876) fasta scores: E(): 0, 29.9% in 551 aa. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature; Similar to ML1089, ML1424, ML0848 a [...] | 0.682 |
ML1149 | cobT | gene:17574976 | gene:17574694 | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD14_MYCLE (P53523) (191 aa); Fasta score E(): 0, 100.0% identity in 191 aa overlap. Also similar to many other proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv1314c SW:YD14_MYCTU (Q10622) (193 aa); Fasta score E(): 0, 81.2% identity in 191 aa overlap. Contains Pfam match to entry PF01923 DUF80, Protein of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | Putative nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.721 |
ML1149 | metH | gene:17574976 | gene:17575141 | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD14_MYCLE (P53523) (191 aa); Fasta score E(): 0, 100.0% identity in 191 aa overlap. Also similar to many other proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv1314c SW:YD14_MYCTU (Q10622) (193 aa); Fasta score E(): 0, 81.2% identity in 191 aa overlap. Contains Pfam match to entry PF01923 DUF80, Protein of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | 5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). | 0.458 |
ML1149 | murA | gene:17574976 | gene:17574977 | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD14_MYCLE (P53523) (191 aa); Fasta score E(): 0, 100.0% identity in 191 aa overlap. Also similar to many other proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv1314c SW:YD14_MYCTU (Q10622) (193 aa); Fasta score E(): 0, 81.2% identity in 191 aa overlap. Contains Pfam match to entry PF01923 DUF80, Protein of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | UDP-N-acetylglucosamine-1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.743 |
ML2084 | ML1005 | gene:17575936 | gene:17574831 | Probable multidrug resistance pump; Similar to Mycobacterium tuberculosis hypothetical ABC transporter ATP-binding protein Rv1819c SW:YI19_MYCTU (Q50614) fasta scores: E(): 0, 74.9% in 634 aa, and in C-term to Escherichia coli hypothetical ABC transporter ATP-binding protein in pqql-hipa intergenic region SW:YDDA_ECOLI (P31826; P76133; P76876) fasta scores: E(): 0, 29.9% in 551 aa. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature; Similar to ML1089, ML1424, ML0848 a [...] | Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.550 |
ML2084 | ML1149 | gene:17575936 | gene:17574976 | Probable multidrug resistance pump; Similar to Mycobacterium tuberculosis hypothetical ABC transporter ATP-binding protein Rv1819c SW:YI19_MYCTU (Q50614) fasta scores: E(): 0, 74.9% in 634 aa, and in C-term to Escherichia coli hypothetical ABC transporter ATP-binding protein in pqql-hipa intergenic region SW:YDDA_ECOLI (P31826; P76133; P76876) fasta scores: E(): 0, 29.9% in 551 aa. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature; Similar to ML1089, ML1424, ML0848 a [...] | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD14_MYCLE (P53523) (191 aa); Fasta score E(): 0, 100.0% identity in 191 aa overlap. Also similar to many other proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv1314c SW:YD14_MYCTU (Q10622) (193 aa); Fasta score E(): 0, 81.2% identity in 191 aa overlap. Contains Pfam match to entry PF01923 DUF80, Protein of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.682 |
ML2084 | cobT | gene:17575936 | gene:17574694 | Probable multidrug resistance pump; Similar to Mycobacterium tuberculosis hypothetical ABC transporter ATP-binding protein Rv1819c SW:YI19_MYCTU (Q50614) fasta scores: E(): 0, 74.9% in 634 aa, and in C-term to Escherichia coli hypothetical ABC transporter ATP-binding protein in pqql-hipa intergenic region SW:YDDA_ECOLI (P31826; P76133; P76876) fasta scores: E(): 0, 29.9% in 551 aa. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature; Similar to ML1089, ML1424, ML0848 a [...] | Putative nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.751 |
cobT | ML1005 | gene:17574694 | gene:17574831 | Putative nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.684 |
cobT | ML1149 | gene:17574694 | gene:17574976 | Putative nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD14_MYCLE (P53523) (191 aa); Fasta score E(): 0, 100.0% identity in 191 aa overlap. Also similar to many other proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv1314c SW:YD14_MYCTU (Q10622) (193 aa); Fasta score E(): 0, 81.2% identity in 191 aa overlap. Contains Pfam match to entry PF01923 DUF80, Protein of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.721 |
cobT | ML2084 | gene:17574694 | gene:17575936 | Putative nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | Probable multidrug resistance pump; Similar to Mycobacterium tuberculosis hypothetical ABC transporter ATP-binding protein Rv1819c SW:YI19_MYCTU (Q50614) fasta scores: E(): 0, 74.9% in 634 aa, and in C-term to Escherichia coli hypothetical ABC transporter ATP-binding protein in pqql-hipa intergenic region SW:YDDA_ECOLI (P31826; P76133; P76876) fasta scores: E(): 0, 29.9% in 551 aa. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature; Similar to ML1089, ML1424, ML0848 a [...] | 0.751 |
cobT | metH | gene:17574694 | gene:17575141 | Putative nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). | 0.485 |
metH | ML1149 | gene:17575141 | gene:17574976 | 5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD14_MYCLE (P53523) (191 aa); Fasta score E(): 0, 100.0% identity in 191 aa overlap. Also similar to many other proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv1314c SW:YD14_MYCTU (Q10622) (193 aa); Fasta score E(): 0, 81.2% identity in 191 aa overlap. Contains Pfam match to entry PF01923 DUF80, Protein of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.458 |
metH | cobT | gene:17575141 | gene:17574694 | 5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). | Putative nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.485 |
murA | ML1149 | gene:17574977 | gene:17574976 | UDP-N-acetylglucosamine-1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD14_MYCLE (P53523) (191 aa); Fasta score E(): 0, 100.0% identity in 191 aa overlap. Also similar to many other proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein Rv1314c SW:YD14_MYCTU (Q10622) (193 aa); Fasta score E(): 0, 81.2% identity in 191 aa overlap. Contains Pfam match to entry PF01923 DUF80, Protein of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.743 |