node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ML0542 | ML1064 | gene:17574363 | gene:17574890 | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49955 (EMBL:U15180) (318 aa); Fasta score E(): 0, 100.0% identity in 317 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv1208 TR:O05309 (EMBL:Z93777) (324 aa); Fasta score E(): 0, 79.8% identity in 327 aa overlap. | 0.798 |
ML0542 | cysS2 | gene:17574363 | gene:17575136 | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | cysteinyl-tRNA synthase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 0.828 |
ML0542 | lsr2 | gene:17574363 | gene:17574051 | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | Lsr2 protein (15 kDa antigen); DNA-bridging protein that has both architectural and regulatory roles. Influences the organization of chromatin and gene expression by binding non-specifically to DNA, with a preference for AT-rich sequences, and bridging distant DNA segments. Represses expression of multiple genes involved in a broad range of cellular processes. May coordinate global gene regulation and virulence as well as genes important for adaptation to changing O(2) levels. Protects against reactive oxygen intermediates (By similarity). Dominant T-cell antigen and stimulates lymphop [...] | 0.842 |
ML0542 | mrsA | gene:17574363 | gene:17574185 | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | Putative phosphoglucomutase/phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.845 |
ML1064 | ML0542 | gene:17574890 | gene:17574363 | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49955 (EMBL:U15180) (318 aa); Fasta score E(): 0, 100.0% identity in 317 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv1208 TR:O05309 (EMBL:Z93777) (324 aa); Fasta score E(): 0, 79.8% identity in 327 aa overlap. | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.798 |
ML1064 | cysS2 | gene:17574890 | gene:17575136 | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49955 (EMBL:U15180) (318 aa); Fasta score E(): 0, 100.0% identity in 317 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv1208 TR:O05309 (EMBL:Z93777) (324 aa); Fasta score E(): 0, 79.8% identity in 327 aa overlap. | cysteinyl-tRNA synthase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 0.798 |
ML1064 | mrsA | gene:17574890 | gene:17574185 | Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49955 (EMBL:U15180) (318 aa); Fasta score E(): 0, 100.0% identity in 317 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv1208 TR:O05309 (EMBL:Z93777) (324 aa); Fasta score E(): 0, 79.8% identity in 327 aa overlap. | Putative phosphoglucomutase/phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.808 |
ML1299 | ML1300 | gene:17575133 | gene:17575134 | Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2134C TR:O06241 (EMBL:Z95388) (195 aa); Fasta score E(): 0, 91.1% identity in 192 aa overlap. | Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2133C TR:O06242 (EMBL:Z95388) (262 aa); Fasta score E(): 0, 79.4% identity in 262 aa overlap. | 0.965 |
ML1299 | ML1495 | gene:17575133 | gene:17575335 | Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2134C TR:O06241 (EMBL:Z95388) (195 aa); Fasta score E(): 0, 91.1% identity in 192 aa overlap. | Conserved hypothetical protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | 0.542 |
ML1299 | cysS2 | gene:17575133 | gene:17575136 | Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2134C TR:O06241 (EMBL:Z95388) (195 aa); Fasta score E(): 0, 91.1% identity in 192 aa overlap. | cysteinyl-tRNA synthase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 0.777 |
ML1300 | ML1299 | gene:17575134 | gene:17575133 | Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2133C TR:O06242 (EMBL:Z95388) (262 aa); Fasta score E(): 0, 79.4% identity in 262 aa overlap. | Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2134C TR:O06241 (EMBL:Z95388) (195 aa); Fasta score E(): 0, 91.1% identity in 192 aa overlap. | 0.965 |
ML1300 | ML1495 | gene:17575134 | gene:17575335 | Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2133C TR:O06242 (EMBL:Z95388) (262 aa); Fasta score E(): 0, 79.4% identity in 262 aa overlap. | Conserved hypothetical protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | 0.641 |
ML1300 | ML2193 | gene:17575134 | gene:17576050 | Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2133C TR:O06242 (EMBL:Z95388) (262 aa); Fasta score E(): 0, 79.4% identity in 262 aa overlap. | Putative acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. | 0.436 |
ML1300 | ML2391 | gene:17575134 | gene:17576253 | Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2133C TR:O06242 (EMBL:Z95388) (262 aa); Fasta score E(): 0, 79.4% identity in 262 aa overlap. | Conserved hypothetical protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | 0.499 |
ML1300 | cysS2 | gene:17575134 | gene:17575136 | Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2133C TR:O06242 (EMBL:Z95388) (262 aa); Fasta score E(): 0, 79.4% identity in 262 aa overlap. | cysteinyl-tRNA synthase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 0.777 |
ML1495 | ML1299 | gene:17575335 | gene:17575133 | Conserved hypothetical protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2134C TR:O06241 (EMBL:Z95388) (195 aa); Fasta score E(): 0, 91.1% identity in 192 aa overlap. | 0.542 |
ML1495 | ML1300 | gene:17575335 | gene:17575134 | Conserved hypothetical protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2133C TR:O06242 (EMBL:Z95388) (262 aa); Fasta score E(): 0, 79.4% identity in 262 aa overlap. | 0.641 |
ML1495 | ML2193 | gene:17575335 | gene:17576050 | Conserved hypothetical protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | Putative acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. | 0.974 |
ML1495 | ML2391 | gene:17575335 | gene:17576253 | Conserved hypothetical protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | Conserved hypothetical protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | 0.436 |
ML1495 | ML2443 | gene:17575335 | gene:17576306 | Conserved hypothetical protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | Possible glycosyl transferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 0.957 |