STRINGSTRING
ML1370 protein (Mycobacterium leprae) - STRING interaction network
"ML1370" - Pseudouridine synthase in Mycobacterium leprae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ML1370Pseudouridine synthase (257 aa)    
Predicted Functional Partners:
der
GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis (462 aa)
 
   
  0.942
ML1369
Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (231 aa)
   
   
  0.918
cmk
Cytidylate kinase (223 aa)
   
        0.882
ML1368
Hypothetical protein (268 aa)
   
   
  0.814
ML1367
Regulatory protein (287 aa)
   
        0.788
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (320 aa)
 
   
  0.645
ML1664
Hypothetical protein (157 aa)
   
        0.619
efp
Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (187 aa)
 
      0.593
ML1512
Hypothetical protein (558 aa)
   
        0.552
rpsA
30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) (481 aa)
   
      0.551
Your Current Organism:
Mycobacterium leprae
NCBI taxonomy Id: 272631
Other names: Bacillus leprae, M. leprae, M. leprae TN, Mycobacterium leprae, Mycobacterium leprae TN, Mycobacterium leprae str. TN, Mycobacterium leprae strain TN, Mycoplasma leprae
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