node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ML0563 | ML1468 | gene:17574384 | gene:17575306 | Conserved hypothetical protein; Displays ATPase and GTPase activities. | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | 0.546 |
ML1468 | ML0563 | gene:17575306 | gene:17574384 | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | Conserved hypothetical protein; Displays ATPase and GTPase activities. | 0.546 |
ML1468 | ML1512 | gene:17575306 | gene:17575353 | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | 0.798 |
ML1468 | ML2709 | gene:17575306 | gene:17576575 | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | Conserved hypothetical protein; Similar to Mycobacterium paratuberculosis hypothetical 20.1 kda protein TR:AAF33691 (EMBL:AF222789) fasta scores: E(): 0, 76.0% in 183 aa, and to Mycobacterium tuberculosis hypothetical 20.6 kda protein TR:O53598 (EMBL:AL021426) fasta scores: E(): 0, 73.1% in 193 aa. Contains Pfam match to entry PF01424 R3H, R3H domain. | 0.499 |
ML1468 | eno | gene:17575306 | gene:17574073 | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.569 |
ML1468 | gpsI | gene:17575306 | gene:17574680 | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | Putative polyribonucleotide phosphorylase / guanosine pentaphosphate synthetase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.942 |
ML1468 | proB | gene:17575306 | gene:17575302 | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.633 |
ML1468 | rhlE | gene:17575306 | gene:17574636 | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | Similar to Mycobacterium tuberculosis putative ATP-dependent RNA helicase Rv3211 or MTCY07D11.15c (407 aa) TR:O05855 (EMBL:Z95120) fasta scores: E(): 0, 74.8% id in 531 aa, and to Klebsiella pneumoniae ATP-dependent RNA helicase deaD SW:DEAD_KLEPN (P33906) fasta scores: E(): 0, 43.2% id in 380 aa. Contains Pfam match to entry PF00271 helicase_C, Helicases conserved C-terminal domain. Contains Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00039 DEAD-box subfamily ATP-dependent helicases signature. | 0.867 |
ML1468 | rphA | gene:17575306 | gene:17575004 | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.505 |
ML1468 | rplU | gene:17575306 | gene:17575305 | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.707 |
ML1468 | rpmA | gene:17575306 | gene:17575304 | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | Highly similar to many 50s ribosomal proteins (L27) including: Escherichia coli SW:RL27_ECOLI (P02427) (84 aa); Fasta score E(): 5.8e-16, 63.9% identity in 83 aa overlap and Mycobacterium tuberculosis RV2441C SW:RL27_MYCTU (Z8145) (86 aa); Fasta score E(): 3.3e-28, 93.8% identity in 81 aa overlap. Contains Pfam match to entry PF01016 Ribosomal_L27, Ribosomal L27 protein. Contains PS00831 Ribosomal protein L27 signature; Belongs to the bacterial ribosomal protein bL27 family. | 0.692 |
ML1512 | ML1468 | gene:17575353 | gene:17575306 | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | 0.798 |
ML1512 | ML2709 | gene:17575353 | gene:17576575 | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | Conserved hypothetical protein; Similar to Mycobacterium paratuberculosis hypothetical 20.1 kda protein TR:AAF33691 (EMBL:AF222789) fasta scores: E(): 0, 76.0% in 183 aa, and to Mycobacterium tuberculosis hypothetical 20.6 kda protein TR:O53598 (EMBL:AL021426) fasta scores: E(): 0, 73.1% in 193 aa. Contains Pfam match to entry PF01424 R3H, R3H domain. | 0.444 |
ML1512 | gpsI | gene:17575353 | gene:17574680 | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | Putative polyribonucleotide phosphorylase / guanosine pentaphosphate synthetase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.835 |
ML1512 | rhlE | gene:17575353 | gene:17574636 | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | Similar to Mycobacterium tuberculosis putative ATP-dependent RNA helicase Rv3211 or MTCY07D11.15c (407 aa) TR:O05855 (EMBL:Z95120) fasta scores: E(): 0, 74.8% id in 531 aa, and to Klebsiella pneumoniae ATP-dependent RNA helicase deaD SW:DEAD_KLEPN (P33906) fasta scores: E(): 0, 43.2% id in 380 aa. Contains Pfam match to entry PF00271 helicase_C, Helicases conserved C-terminal domain. Contains Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00039 DEAD-box subfamily ATP-dependent helicases signature. | 0.841 |
ML2709 | ML1468 | gene:17576575 | gene:17575306 | Conserved hypothetical protein; Similar to Mycobacterium paratuberculosis hypothetical 20.1 kda protein TR:AAF33691 (EMBL:AF222789) fasta scores: E(): 0, 76.0% in 183 aa, and to Mycobacterium tuberculosis hypothetical 20.6 kda protein TR:O53598 (EMBL:AL021426) fasta scores: E(): 0, 73.1% in 193 aa. Contains Pfam match to entry PF01424 R3H, R3H domain. | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | 0.499 |
ML2709 | ML1512 | gene:17576575 | gene:17575353 | Conserved hypothetical protein; Similar to Mycobacterium paratuberculosis hypothetical 20.1 kda protein TR:AAF33691 (EMBL:AF222789) fasta scores: E(): 0, 76.0% in 183 aa, and to Mycobacterium tuberculosis hypothetical 20.6 kda protein TR:O53598 (EMBL:AL021426) fasta scores: E(): 0, 73.1% in 193 aa. Contains Pfam match to entry PF01424 R3H, R3H domain. | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | 0.444 |
eno | ML1468 | gene:17574073 | gene:17575306 | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | 0.569 |
eno | gpsI | gene:17574073 | gene:17574680 | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Putative polyribonucleotide phosphorylase / guanosine pentaphosphate synthetase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.706 |
eno | rhlE | gene:17574073 | gene:17574636 | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Similar to Mycobacterium tuberculosis putative ATP-dependent RNA helicase Rv3211 or MTCY07D11.15c (407 aa) TR:O05855 (EMBL:Z95120) fasta scores: E(): 0, 74.8% id in 531 aa, and to Klebsiella pneumoniae ATP-dependent RNA helicase deaD SW:DEAD_KLEPN (P33906) fasta scores: E(): 0, 43.2% id in 380 aa. Contains Pfam match to entry PF00271 helicase_C, Helicases conserved C-terminal domain. Contains Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00039 DEAD-box subfamily ATP-dependent helicases signature. | 0.512 |