node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ML1589 | ML1591 | gene:17575430 | gene:17575432 | Possible phosphatidate cytidylyltransferase; The C-terminus of this protein is highly similar to many proteins involved with phospholipid biosynthesis e.g. Escherichia coli phosphatidate cytidylyltransferase (EC 2.7.7.41) SW:CDSA_ECOLI (P06466) (249 aa); Fasta score E(): 6.6e-15, 40.6% identity in 160 aa overlap and Mycobacterium tuberculosis Rv2881c SW:CDSA_MYCTU (Q10807) (306 aa); Fasta score E(): 0, 70.3% identity in 313 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01148 Cytidylyltrans, Phosphatidate cytidylyltransferas [...] | Possible uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.824 |
ML1589 | frr | gene:17575430 | gene:17575431 | Possible phosphatidate cytidylyltransferase; The C-terminus of this protein is highly similar to many proteins involved with phospholipid biosynthesis e.g. Escherichia coli phosphatidate cytidylyltransferase (EC 2.7.7.41) SW:CDSA_ECOLI (P06466) (249 aa); Fasta score E(): 6.6e-15, 40.6% identity in 160 aa overlap and Mycobacterium tuberculosis Rv2881c SW:CDSA_MYCTU (Q10807) (306 aa); Fasta score E(): 0, 70.3% identity in 313 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01148 Cytidylyltrans, Phosphatidate cytidylyltransferas [...] | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.846 |
ML1591 | ML1589 | gene:17575432 | gene:17575430 | Possible uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Possible phosphatidate cytidylyltransferase; The C-terminus of this protein is highly similar to many proteins involved with phospholipid biosynthesis e.g. Escherichia coli phosphatidate cytidylyltransferase (EC 2.7.7.41) SW:CDSA_ECOLI (P06466) (249 aa); Fasta score E(): 6.6e-15, 40.6% identity in 160 aa overlap and Mycobacterium tuberculosis Rv2881c SW:CDSA_MYCTU (Q10807) (306 aa); Fasta score E(): 0, 70.3% identity in 313 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01148 Cytidylyltrans, Phosphatidate cytidylyltransferas [...] | 0.824 |
ML1591 | adk | gene:17575432 | gene:17575680 | Possible uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Probable adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.802 |
ML1591 | atpH | gene:17575432 | gene:17574969 | Possible uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Bi-domained ATP synthase B, [Delta] chain protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). | 0.923 |
ML1591 | frr | gene:17575432 | gene:17575431 | Possible uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.977 |
ML1591 | ndk | gene:17575432 | gene:17575307 | Possible uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.924 |
ML1591 | pyrF | gene:17575432 | gene:17574358 | Possible uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Similar to M. tuberculosis pyrF, Rv1385, orotidine 5'-phosphate decarboxylase, SW:DCOP_MYCTU (P77898) (274 aa); Fasta score E(): 0, 77.3% identity in 282 aa overlap. Similar to many e.g. Mycobacterium smegmatis pyrF, orotidine 5'-phosphate decarboxylase, SW:DCOP_MYCSM (O08323) (276 aa); Fasta score E(): 0, 72.5% identity in 280 aa overlap. Contains Pfam match to entry PF00215 OMPdecase, Orotidine 5'-phosphate decarboxylases. Contains PS00156 Orotidine 5'-phosphate decarboxylase active site; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.930 |
ML1591 | rplS | gene:17575432 | gene:17575454 | Possible uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.787 |
ML1591 | rpsB | gene:17575432 | gene:17575439 | Possible uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Highly similar to many 30s ribosomal proteins (S2) including: Bacillus subtilis SW:RS2_BACSU (P21464) (245 aa); Fasta score E(): 0, 57.6% identity in 250 aa overlap and Mycobacterium tuberculosis RV2890C SW:RS2_MYCTU (Q10796) (287 aa); Fasta score E(): 0, 91.5% identity in 270 aa overlap. Contains Pfam match to entry PF00318 Ribosomal_S2, Ribosomal protein S2. Contains PS00962 Ribosomal protein S2 signature 1; Belongs to the universal ribosomal protein uS2 family. | 0.870 |
ML1591 | rpsJ | gene:17575432 | gene:17575712 | Possible uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.777 |
ML1591 | tsf | gene:17575432 | gene:17575438 | Possible uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity); Belongs to the EF-Ts family. | 0.884 |
adk | ML1591 | gene:17575680 | gene:17575432 | Probable adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Possible uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.802 |
adk | atpH | gene:17575680 | gene:17574969 | Probable adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Bi-domained ATP synthase B, [Delta] chain protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). | 0.930 |
adk | ndk | gene:17575680 | gene:17575307 | Probable adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.930 |
adk | rplS | gene:17575680 | gene:17575454 | Probable adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.815 |
adk | rpsB | gene:17575680 | gene:17575439 | Probable adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Highly similar to many 30s ribosomal proteins (S2) including: Bacillus subtilis SW:RS2_BACSU (P21464) (245 aa); Fasta score E(): 0, 57.6% identity in 250 aa overlap and Mycobacterium tuberculosis RV2890C SW:RS2_MYCTU (Q10796) (287 aa); Fasta score E(): 0, 91.5% identity in 270 aa overlap. Contains Pfam match to entry PF00318 Ribosomal_S2, Ribosomal protein S2. Contains PS00962 Ribosomal protein S2 signature 1; Belongs to the universal ribosomal protein uS2 family. | 0.439 |
adk | rpsJ | gene:17575680 | gene:17575712 | Probable adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.749 |
adk | tsf | gene:17575680 | gene:17575438 | Probable adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity); Belongs to the EF-Ts family. | 0.563 |
atpH | ML1591 | gene:17574969 | gene:17575432 | Bi-domained ATP synthase B, [Delta] chain protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). | Possible uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.923 |