node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ML1657 | ML2355 | gene:17575500 | gene:17576217 | Acetyl/propionyl CoA carboxylase [beta] subunit; Highly similar to many propionyl-CoA carboxylases involved in fatty acid catabolism including: Rhodococcus erythropolis SW:PCCB_RHOER (Q06101) (476 aa); Fasta score E(): 0, 70.9% identity in 477 aa overlap and Mycobacterium tuberculosis RV2247 SW:PCCB_MYCTU (Q10506) (473 aa); Fasta score E(): 0, 92.8% identity in 473 aa overlap. Contains Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain. Contains PS00017 ATP/GTP-binding site motif A (P-loop); Similar to ML0731. | Similar to several polyketide synthases e.g. Mycobacterium tuberculosis Rv2933 TR:P96202 (EMBL:Z83857) (2188 aa) fasta scores: E(): 0, 82.3% id in 2217 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00133 Zinc carboxypeptidases. Contains PS00606 Beta-ketoacyl [...] | 0.471 |
ML1657 | ML2357 | gene:17575500 | gene:17576219 | Acetyl/propionyl CoA carboxylase [beta] subunit; Highly similar to many propionyl-CoA carboxylases involved in fatty acid catabolism including: Rhodococcus erythropolis SW:PCCB_RHOER (Q06101) (476 aa); Fasta score E(): 0, 70.9% identity in 477 aa overlap and Mycobacterium tuberculosis RV2247 SW:PCCB_MYCTU (Q10506) (473 aa); Fasta score E(): 0, 92.8% identity in 473 aa overlap. Contains Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain. Contains PS00017 ATP/GTP-binding site motif A (P-loop); Similar to ML0731. | Polyketide synthase; Highly similar to many Prokaryotic and Eukaryotic polyketide synthases including: Mycobacterium tuberculosis phenolpthiocerol synthase rv2931 SW:PPSA_MYCTU (Q10977) (1876 aa) fasta scores: E(): 0, 76.1% id in 1888 aa and to Penicillium patulum 6-methylsalicylic acid synthase SW:MSAS_PENPA (P22367) (1774 aa) fasta scores: E(): 0, 33.8% id in 1823 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains 2 Pfam matches to entry PF00550 pp-binding, Phosphopantethe [...] | 0.413 |
ML1657 | acpM | gene:17575500 | gene:17575497 | Acetyl/propionyl CoA carboxylase [beta] subunit; Highly similar to many propionyl-CoA carboxylases involved in fatty acid catabolism including: Rhodococcus erythropolis SW:PCCB_RHOER (Q06101) (476 aa); Fasta score E(): 0, 70.9% identity in 477 aa overlap and Mycobacterium tuberculosis RV2247 SW:PCCB_MYCTU (Q10506) (473 aa); Fasta score E(): 0, 92.8% identity in 473 aa overlap. Contains Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain. Contains PS00017 ATP/GTP-binding site motif A (P-loop); Similar to ML0731. | Acyl carrier protein (meromycolate extension); Acyl carrier protein involved in meromycolate extension. | 0.903 |
ML1657 | fabD | gene:17575500 | gene:17575496 | Acetyl/propionyl CoA carboxylase [beta] subunit; Highly similar to many propionyl-CoA carboxylases involved in fatty acid catabolism including: Rhodococcus erythropolis SW:PCCB_RHOER (Q06101) (476 aa); Fasta score E(): 0, 70.9% identity in 477 aa overlap and Mycobacterium tuberculosis RV2247 SW:PCCB_MYCTU (Q10506) (473 aa); Fasta score E(): 0, 92.8% identity in 473 aa overlap. Contains Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain. Contains PS00017 ATP/GTP-binding site motif A (P-loop); Similar to ML0731. | Malonyl CoA-[ACP] transacylase; Similar to many malonyl CoA-acyl carrier protein transacylases (EC 2.3.1.39) involved in fatty acid biosynthesis, including: Salmonella typhimurium SW:FABD_SALTY (O85140) (308 aa); Fasta score E(): 1.6e-19, 32.7% identity in 303 aa overlap and Mycobacterium tuberculosis SW:FABD_MYCTU (Q10501) (302 aa); Fasta score E(): 0, 82.2% identity in 304 aa overlap. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. | 0.994 |
ML1657 | kasA | gene:17575500 | gene:17575498 | Acetyl/propionyl CoA carboxylase [beta] subunit; Highly similar to many propionyl-CoA carboxylases involved in fatty acid catabolism including: Rhodococcus erythropolis SW:PCCB_RHOER (Q06101) (476 aa); Fasta score E(): 0, 70.9% identity in 477 aa overlap and Mycobacterium tuberculosis RV2247 SW:PCCB_MYCTU (Q10506) (473 aa); Fasta score E(): 0, 92.8% identity in 473 aa overlap. Contains Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain. Contains PS00017 ATP/GTP-binding site motif A (P-loop); Similar to ML0731. | 3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.987 |
ML1657 | kasB | gene:17575500 | gene:17575499 | Acetyl/propionyl CoA carboxylase [beta] subunit; Highly similar to many propionyl-CoA carboxylases involved in fatty acid catabolism including: Rhodococcus erythropolis SW:PCCB_RHOER (Q06101) (476 aa); Fasta score E(): 0, 70.9% identity in 477 aa overlap and Mycobacterium tuberculosis RV2247 SW:PCCB_MYCTU (Q10506) (473 aa); Fasta score E(): 0, 92.8% identity in 473 aa overlap. Contains Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain. Contains PS00017 ATP/GTP-binding site motif A (P-loop); Similar to ML0731. | 3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.985 |
ML2355 | ML1657 | gene:17576217 | gene:17575500 | Similar to several polyketide synthases e.g. Mycobacterium tuberculosis Rv2933 TR:P96202 (EMBL:Z83857) (2188 aa) fasta scores: E(): 0, 82.3% id in 2217 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00133 Zinc carboxypeptidases. Contains PS00606 Beta-ketoacyl [...] | Acetyl/propionyl CoA carboxylase [beta] subunit; Highly similar to many propionyl-CoA carboxylases involved in fatty acid catabolism including: Rhodococcus erythropolis SW:PCCB_RHOER (Q06101) (476 aa); Fasta score E(): 0, 70.9% identity in 477 aa overlap and Mycobacterium tuberculosis RV2247 SW:PCCB_MYCTU (Q10506) (473 aa); Fasta score E(): 0, 92.8% identity in 473 aa overlap. Contains Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain. Contains PS00017 ATP/GTP-binding site motif A (P-loop); Similar to ML0731. | 0.471 |
ML2355 | ML2357 | gene:17576217 | gene:17576219 | Similar to several polyketide synthases e.g. Mycobacterium tuberculosis Rv2933 TR:P96202 (EMBL:Z83857) (2188 aa) fasta scores: E(): 0, 82.3% id in 2217 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00133 Zinc carboxypeptidases. Contains PS00606 Beta-ketoacyl [...] | Polyketide synthase; Highly similar to many Prokaryotic and Eukaryotic polyketide synthases including: Mycobacterium tuberculosis phenolpthiocerol synthase rv2931 SW:PPSA_MYCTU (Q10977) (1876 aa) fasta scores: E(): 0, 76.1% id in 1888 aa and to Penicillium patulum 6-methylsalicylic acid synthase SW:MSAS_PENPA (P22367) (1774 aa) fasta scores: E(): 0, 33.8% id in 1823 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains 2 Pfam matches to entry PF00550 pp-binding, Phosphopantethe [...] | 0.999 |
ML2355 | ahpC | gene:17576217 | gene:17575894 | Similar to several polyketide synthases e.g. Mycobacterium tuberculosis Rv2933 TR:P96202 (EMBL:Z83857) (2188 aa) fasta scores: E(): 0, 82.3% id in 2217 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00133 Zinc carboxypeptidases. Contains PS00606 Beta-ketoacyl [...] | Alkyl hydroperoxide reductase; Similar to Mycobacterium avium alkyl hydroperoxidase C TR:Q57413 (EMBL:U18263) fasta scores: E(): 0, 86.2% in 195 aa, and to Streptomyces viridosporus alkyl hydroperoxide reductase TR:Q9X5V0 (EMBL:AF127576) fasta scores: E(): 0, 58.7% in 189 aa. Contains Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family. | 0.479 |
ML2355 | fabD | gene:17576217 | gene:17575496 | Similar to several polyketide synthases e.g. Mycobacterium tuberculosis Rv2933 TR:P96202 (EMBL:Z83857) (2188 aa) fasta scores: E(): 0, 82.3% id in 2217 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00133 Zinc carboxypeptidases. Contains PS00606 Beta-ketoacyl [...] | Malonyl CoA-[ACP] transacylase; Similar to many malonyl CoA-acyl carrier protein transacylases (EC 2.3.1.39) involved in fatty acid biosynthesis, including: Salmonella typhimurium SW:FABD_SALTY (O85140) (308 aa); Fasta score E(): 1.6e-19, 32.7% identity in 303 aa overlap and Mycobacterium tuberculosis SW:FABD_MYCTU (Q10501) (302 aa); Fasta score E(): 0, 82.2% identity in 304 aa overlap. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. | 0.999 |
ML2355 | fabG1 | gene:17576217 | gene:17575654 | Similar to several polyketide synthases e.g. Mycobacterium tuberculosis Rv2933 TR:P96202 (EMBL:Z83857) (2188 aa) fasta scores: E(): 0, 82.3% id in 2217 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00133 Zinc carboxypeptidases. Contains PS00606 Beta-ketoacyl [...] | 3-oxoacyl-[ACP] reductase (aka MabA); Similar to M. tuberculosis fabG Rv1483 SW:FABG_MYCTU (Q48930) (247 aa); Fasta score E(): 0, 68.6% identity in 245 aa overlap, and to many others e.g. Escherichia coli fabG 3-oxoacyl-[acyl-carrier protein] reductase SW:FABG_ECOLI (P25716) (244 aa); Fasta score E(): 0, 47.3% identity in 241 aa overlap. Contains Pfam match to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature; Simil [...] | 0.518 |
ML2355 | fadD32 | gene:17576217 | gene:17573912 | Similar to several polyketide synthases e.g. Mycobacterium tuberculosis Rv2933 TR:P96202 (EMBL:Z83857) (2188 aa) fasta scores: E(): 0, 82.3% id in 2217 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00133 Zinc carboxypeptidases. Contains PS00606 Beta-ketoacyl [...] | Similar to several putative acyl-CoA synthases from M. tuberculosis e.g. M. tuberculosis Rv3801c, fadD32, putative acyl-CoA synthase, TR:O53580 (EMBL:AL123456) (637 aa); Fasta score E(): 0, 93.2% identity in 632 aa overlap. Similar to Mycobacterium bovis BCG ORF3, acyl-CoA synthase, TR:P71495 (EMBL:U75685) (582 aa); Fasta score E(): 0, 36.8% identity in 581 aa overlap and to domains of polyketide synthases e.g. Myxococcus xanthus safB, saframycin Mx1 synthetase B, TR:Q50857 (EMBL:U24657) (1770 aa); Fasta score E(): 0, 36.4% identity in 605 aa overlap. Contains Pfam match to entry PF005 [...] | 0.815 |
ML2355 | inhA | gene:17576217 | gene:17575653 | Similar to several polyketide synthases e.g. Mycobacterium tuberculosis Rv2933 TR:P96202 (EMBL:Z83857) (2188 aa) fasta scores: E(): 0, 82.3% id in 2217 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00133 Zinc carboxypeptidases. Contains PS00606 Beta-ketoacyl [...] | enoyl-[ACP] reductase; Similar to M. tuberculosis inhA Rv1484 SW:INHA_MYCTU (P46533) (269 aa); Fasta score E(): 0, 90.3% identity in 269 aa overlap, and to many others e.g. Escherichia coli enoyl-[acyl-carrier-protein] reductase [NADH] SW:FABI_ECOLI (P29132) (261 aa); Fasta score E(): 1.2e-17, 33.2% identity in 268 aa overlap; Similar to and ML1807. | 0.741 |
ML2355 | kasA | gene:17576217 | gene:17575498 | Similar to several polyketide synthases e.g. Mycobacterium tuberculosis Rv2933 TR:P96202 (EMBL:Z83857) (2188 aa) fasta scores: E(): 0, 82.3% id in 2217 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00133 Zinc carboxypeptidases. Contains PS00606 Beta-ketoacyl [...] | 3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.894 |
ML2355 | kasB | gene:17576217 | gene:17575499 | Similar to several polyketide synthases e.g. Mycobacterium tuberculosis Rv2933 TR:P96202 (EMBL:Z83857) (2188 aa) fasta scores: E(): 0, 82.3% id in 2217 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00133 Zinc carboxypeptidases. Contains PS00606 Beta-ketoacyl [...] | 3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.894 |
ML2357 | ML1657 | gene:17576219 | gene:17575500 | Polyketide synthase; Highly similar to many Prokaryotic and Eukaryotic polyketide synthases including: Mycobacterium tuberculosis phenolpthiocerol synthase rv2931 SW:PPSA_MYCTU (Q10977) (1876 aa) fasta scores: E(): 0, 76.1% id in 1888 aa and to Penicillium patulum 6-methylsalicylic acid synthase SW:MSAS_PENPA (P22367) (1774 aa) fasta scores: E(): 0, 33.8% id in 1823 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains 2 Pfam matches to entry PF00550 pp-binding, Phosphopantethe [...] | Acetyl/propionyl CoA carboxylase [beta] subunit; Highly similar to many propionyl-CoA carboxylases involved in fatty acid catabolism including: Rhodococcus erythropolis SW:PCCB_RHOER (Q06101) (476 aa); Fasta score E(): 0, 70.9% identity in 477 aa overlap and Mycobacterium tuberculosis RV2247 SW:PCCB_MYCTU (Q10506) (473 aa); Fasta score E(): 0, 92.8% identity in 473 aa overlap. Contains Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain. Contains PS00017 ATP/GTP-binding site motif A (P-loop); Similar to ML0731. | 0.413 |
ML2357 | ML2355 | gene:17576219 | gene:17576217 | Polyketide synthase; Highly similar to many Prokaryotic and Eukaryotic polyketide synthases including: Mycobacterium tuberculosis phenolpthiocerol synthase rv2931 SW:PPSA_MYCTU (Q10977) (1876 aa) fasta scores: E(): 0, 76.1% id in 1888 aa and to Penicillium patulum 6-methylsalicylic acid synthase SW:MSAS_PENPA (P22367) (1774 aa) fasta scores: E(): 0, 33.8% id in 1823 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains 2 Pfam matches to entry PF00550 pp-binding, Phosphopantethe [...] | Similar to several polyketide synthases e.g. Mycobacterium tuberculosis Rv2933 TR:P96202 (EMBL:Z83857) (2188 aa) fasta scores: E(): 0, 82.3% id in 2217 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00133 Zinc carboxypeptidases. Contains PS00606 Beta-ketoacyl [...] | 0.999 |
ML2357 | fabD | gene:17576219 | gene:17575496 | Polyketide synthase; Highly similar to many Prokaryotic and Eukaryotic polyketide synthases including: Mycobacterium tuberculosis phenolpthiocerol synthase rv2931 SW:PPSA_MYCTU (Q10977) (1876 aa) fasta scores: E(): 0, 76.1% id in 1888 aa and to Penicillium patulum 6-methylsalicylic acid synthase SW:MSAS_PENPA (P22367) (1774 aa) fasta scores: E(): 0, 33.8% id in 1823 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains 2 Pfam matches to entry PF00550 pp-binding, Phosphopantethe [...] | Malonyl CoA-[ACP] transacylase; Similar to many malonyl CoA-acyl carrier protein transacylases (EC 2.3.1.39) involved in fatty acid biosynthesis, including: Salmonella typhimurium SW:FABD_SALTY (O85140) (308 aa); Fasta score E(): 1.6e-19, 32.7% identity in 303 aa overlap and Mycobacterium tuberculosis SW:FABD_MYCTU (Q10501) (302 aa); Fasta score E(): 0, 82.2% identity in 304 aa overlap. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. | 0.999 |
ML2357 | fadD32 | gene:17576219 | gene:17573912 | Polyketide synthase; Highly similar to many Prokaryotic and Eukaryotic polyketide synthases including: Mycobacterium tuberculosis phenolpthiocerol synthase rv2931 SW:PPSA_MYCTU (Q10977) (1876 aa) fasta scores: E(): 0, 76.1% id in 1888 aa and to Penicillium patulum 6-methylsalicylic acid synthase SW:MSAS_PENPA (P22367) (1774 aa) fasta scores: E(): 0, 33.8% id in 1823 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains 2 Pfam matches to entry PF00550 pp-binding, Phosphopantethe [...] | Similar to several putative acyl-CoA synthases from M. tuberculosis e.g. M. tuberculosis Rv3801c, fadD32, putative acyl-CoA synthase, TR:O53580 (EMBL:AL123456) (637 aa); Fasta score E(): 0, 93.2% identity in 632 aa overlap. Similar to Mycobacterium bovis BCG ORF3, acyl-CoA synthase, TR:P71495 (EMBL:U75685) (582 aa); Fasta score E(): 0, 36.8% identity in 581 aa overlap and to domains of polyketide synthases e.g. Myxococcus xanthus safB, saframycin Mx1 synthetase B, TR:Q50857 (EMBL:U24657) (1770 aa); Fasta score E(): 0, 36.4% identity in 605 aa overlap. Contains Pfam match to entry PF005 [...] | 0.835 |
ML2357 | inhA | gene:17576219 | gene:17575653 | Polyketide synthase; Highly similar to many Prokaryotic and Eukaryotic polyketide synthases including: Mycobacterium tuberculosis phenolpthiocerol synthase rv2931 SW:PPSA_MYCTU (Q10977) (1876 aa) fasta scores: E(): 0, 76.1% id in 1888 aa and to Penicillium patulum 6-methylsalicylic acid synthase SW:MSAS_PENPA (P22367) (1774 aa) fasta scores: E(): 0, 33.8% id in 1823 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains 2 Pfam matches to entry PF00550 pp-binding, Phosphopantethe [...] | enoyl-[ACP] reductase; Similar to M. tuberculosis inhA Rv1484 SW:INHA_MYCTU (P46533) (269 aa); Fasta score E(): 0, 90.3% identity in 269 aa overlap, and to many others e.g. Escherichia coli enoyl-[acyl-carrier-protein] reductase [NADH] SW:FABI_ECOLI (P29132) (261 aa); Fasta score E(): 1.2e-17, 33.2% identity in 268 aa overlap; Similar to and ML1807. | 0.737 |